SCHEMBL16355877

SCHEMBL16355877

Oc1ccc(CCc2ccccc2)cc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.60
CA1 P00915 2/20 0.60
HSD17B2 P37059 2/20 0.60
ALOX15 P16050 4/20 0.58
IGF1R P08069 3/20 0.58
ESR2 Q92731 1/20 0.52
ADRB2 P07550 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CHRM1 P11229 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
DRD1 P21728 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
ADRA1A P35348 1/20 0.47
PTGS2 P35354 1/20 0.47
HRH1 P35367 1/20 0.47
DRD3 P35462 1/20 0.47
OPRK1 P41145 1/20 0.47
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9773533 0.89 CA2 (0.61) CA2CA1HSD17B2ALOX15IGF1R
SCHEMBL744471 0.84 IDH1 (0.68) CA2CA1HSD17B2ALOX15ESR2
SCHEMBL11357079 0.82 CA2 (0.53) CA2CA1HSD17B2ALOX15IGF1R
SCHEMBL28128266 0.81 SIGMAR1 (0.60) ALOX15IGF1RSLC6A2SLC6A4SLC6A3
2-Chlorophenol SCHEMBL9482726 0.81 ALDH1A1 (0.68) CA2CA1HSD17B2ALOX15IGF1R
SCHEMBL9745836 0.81 IGF1R (0.66) CA2CA1ALOX15IGF1RCYP3A4
SCHEMBL9744485 0.81 ALOX15 (0.84) ALOX15IGF1RADRB2ADORA3CHRM1
SCHEMBL5792303 0.79 CA2 (0.51) CA2CA1HSD17B2ALOX15IGF1R
SCHEMBL5454185 0.79 KDM4E (0.65) CA2CA1HSD17B2ALOX15IGF1R
SCHEMBL18986912 0.79 CA2 (0.55) CA2CA1HSD17B2ALOX15IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111004385-B Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-04-12 CN disclosed
CN-117659387-A Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-03-08 CN disclosed
CN-117178007-A Phenylether oligomers and curable thermoset compositions comprising the same 高新特殊工程塑料全球技术有限公司 2023-12-05 CN disclosed
CN-111004385-A Poly (arylene ether) copolymers 沙特基础工业全球技术有限公司 2020-04-14 CN disclosed
US-9199927-B2 Guanidinobenzoic acid compound ASTELLAS PHARMA INC. (JP) 2015-12-01 US disclosed
US-20140378459-A1 GUANIDINOBENZOIC ACID COMPOUND ASTELLAS PHARMA INC. (JP) 2014-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378459-A1 GUANIDINOBENZOIC ACID COMPOUND SERPINB1, REN, SPINT2 CA2 801/4885CA1 437/4885HSD17B2 2921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.