SCHEMBL16367348

SCHEMBL16367348

CC(=O)OC(COS(=O)(=O)c1ccc(C)cc1)C(Cn1cccc1[N+](=O)[O-])OC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.34
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
LMNA P02545 2/20 0.33
CYP24A1 Q07973 1/20 0.33
MAPK1 P28482 1/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
STAT3 P40763 1/20 0.32
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
MAPT P10636 1/20 0.31
GPR17 Q13304 1/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16367365 0.89 MMP2 (0.36) DHODHMMP2MMP9LMNACYP24A1
SCHEMBL15607848 0.86 PTGS2 (0.31)
SCHEMBL16367343 0.84 EGFR (0.36) DHODHLMNACYP24A1MAPK1EGFR
SCHEMBL16367377 0.83 ALDH1A1 (0.39) DHODHMMP2MMP9CYP24A1EGFR
SCHEMBL16367378 0.82 MMP2 (0.36) DHODHMMP2MMP9CYP24A1EGFR
SCHEMBL8424432 0.80 DHODH (0.44) DHODHMMP2MMP9LMNAMAPK1
SCHEMBL16367412 0.79 ALDH1A1 (0.34) LMNAALDH1A1
SCHEMBL16367346 0.77 L3MBTL1 (0.37) DHODHLMNAMAPK1EGFRERBB2
SCHEMBL16367408 0.75 ACHE (0.44) MMP2MMP9LMNAALDH1A1PKM
SCHEMBL16367319 0.75 POLB (0.36) MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150010474-A1 Compounds And Methods For Selective Imaging And/Or Ablation AUCKLAND UNISERVICES LTD (NL) 2015-01-08 US disclosed
US-20150010474-A1 Compounds And Methods For Selective Imaging And/Or Ablation AUCKLAND UNISERVICES LTD (NL) 2015-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150010474-A1 Compounds And Methods For Selective Imaging And/Or Ablation CBR1, CBR3, BLVRB DHODH 14/4885MMP2 982/4885MMP9 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.