SCHEMBL163688

SCHEMBL163688

C#Cc1ccc(OCCC)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.52
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
PLK1 P53350 1/20 0.46
LMNA P02545 1/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10988244 0.94 CYP3A4 (0.50) LTA4HCA12CA1CA2CA7
SCHEMBL1007565 0.91 LTA4H (0.53) LTA4HCA12CA1CA2CA7
SCHEMBL949228 0.88 NR5A1 (0.58) LTA4HL3MBTL1LMNANPC1MAPT
SCHEMBL20969950 0.86 PRSS1 (0.41) CA12CA1CA2CA9MAPT
SCHEMBL2832393 0.86 NR5A1 (0.61) LTA4HL3MBTL1LMNANPC1MAPT
SCHEMBL946779 0.86 NR5A1 (0.61) LTA4HL3MBTL1LMNANPC1MAPT
SCHEMBL948700 0.86 NR5A1 (0.61) LTA4HL3MBTL1LMNANPC1MAPT
SCHEMBL9706419 0.86 NR5A1 (0.61) LTA4HL3MBTL1LMNANPC1MAPT
SCHEMBL10993242 0.86 CYP2D6 (0.59) LTA4HL3MBTL1NPC1HPGDRAB9A
SCHEMBL4748828 0.86 NR5A1 (0.61) LTA4HL3MBTL1LMNANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025048243-A1 NOVEL ISOXAZOLE COMPOUND AS TM4SF5-SPECIFIC INHIBITOR AND USE THEREOF 서울대학교산학협력단 2025-03-06 WO disclosed
EP-3733186-B1 NOVEL DIHYDROQUINAZOLINONE COMPOUND OR PHARMACOLOGICALLY ACCEPTABLE SALT, AND CELL GROWTH INHIBITOR JAPANESE FOUND FOR CANCER RES (JP) 2024-12-04 EP disclosed
US-11566017-B2 Dihydroquinazolinone compound or pharmacologically acceptable salt, and cell growth inhibitor RIKEN (JP) 2023-01-31 US disclosed
US-20210061789-A1 NOVEL DIHYDROQUINAZOLINONE COMPOUND OR PHARMACOLOGICALLY ACCEPTABLE SALT, AND CELL GROWTH INHIBITOR RIKEN (JP) 2021-03-04 US disclosed
EP-3733186-A1 NOVEL DIHYDRO-QUINAZOLINONE COMPOUND OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, AND CELL GROWTH INHIBITOR RIKEN (JP) 2020-11-04 EP disclosed
US-20180333406-A1 BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2018-11-22 US disclosed
US-20180086979-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-03-29 US disclosed
EP-1763509-B1 ALPHA-HELICAL MIMETICS WALTER & ELIZA HALL INST MEDICAL RES (AU) 2018-02-21 EP disclosed
US-9896479-B2 Functionalized naphthalene fluorophores Kay M. Brummond (US) 2018-02-20 US disclosed
EP-2440245-B1 BENZONAPHTHYRIDINE-CONTAINING VACCINES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2017-12-06 EP disclosed
WO-2005012280-A1 ALKYNYL ARYL CARBOXAMIDES APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2005-02-10 WO disclosed
EP-1274713-B1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIV CARDIFF (GB) 2004-03-10 EP disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
US-20030148967-A1 Anti-viral pyrimidine nucleoside analogues REGA FOUNDATION (BE) 2003-08-07 US disclosed
EP-1274713-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES University College Cardiff Consultants Limited (GB) 2003-01-15 EP disclosed
WO-2001083501-A1 ANTI-VIRAL PYRIMIDINE NUCLEOSIDE ANALOGUES UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2001-11-08 WO disclosed
EP-0597701-B1 Conjugated enyne derivative and liquid crystal composition CHISSO CORP (JP) 1997-04-16 EP disclosed
US-5370819-A Low viscosity CHISSO CORPORATION (JP) 1994-12-06 US disclosed
EP-0597701-A1 Conjugated enyne derivative and liquid crystal composition CHISSO CORPORATION (JP) 1994-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061789-A1 NOVEL DIHYDROQUINAZOLINONE COMPOUND OR PHARMACOLOGICALLY ACCEPTABLE SALT, AND CELL GROWTH INHIBITOR MKI67, CCNI, NHERF1 LTA4H 4407/4885CA12 1887/4885CA1 1463/4885
US-20030148967-A1 Anti-viral pyrimidine nucleoside analogues NUDT1, DNTT, RNMT LTA4H 2687/4885CA12 2264/4885CA1 3448/4885
US-11566017-B2 Dihydroquinazolinone compound or pharmacologically acceptable salt, and cell growth inhibitor MKI67, CCNI, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 LTA4H 4415/4885CA12 1568/4885CA1 1322/4885
US-20180333406-A1 BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF HAMP, MAVS, MYD88 LTA4H 2416/4885CA12 3836/4885CA1 4263/4885
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM LTA4H 1238/4885CA12 4194/4885CA1 1984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.