SCHEMBL16369461

SCHEMBL16369461

Cc1ncc2c(c1C)-c1ccccc1C2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRE P78334 1/20 0.40
GABRA6 Q16445 1/20 0.40
GABRG1 Q8N1C3 1/20 0.40
GABRG3 Q99928 1/20 0.40
GABRQ Q9UN88 1/20 0.40
PLK4 O00444 1/20 0.40
DAPK3 O43293 1/20 0.40
PIM1 P11309 1/20 0.40
PDGFRA P16234 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26267001 0.79 METAP1 (0.40) KDM4EMAPTRAB9ASMN1; SMN2ALDH1A1
SCHEMBL26267000 0.79 METAP1 (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26267037 0.78 CCR1 (0.33) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26267002 0.78 ACHE (0.35) ALDH1A1ADRA2AADRA1ATYMS
SCHEMBL26266999 0.77 HTR5A (0.33) MAPTSMN1; SMN2ALDH1A1HPGDKMT2A
SCHEMBL26267016 0.75
SCHEMBL16369460 0.75 PNMT (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL26267009 0.73 AKT1 (0.36)
SCHEMBL26266786 0.72 TDP2 (0.32)
SCHEMBL18416164 0.71 GABRP (0.36) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018037-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-06-25 US disclosed
US-20230371359-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-16 US disclosed
US-11758803-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-12 US disclosed
US-20230276692-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-31 US disclosed
US-20230276693-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND MIXTURE SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-31 US disclosed
US-11731994-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-22 US disclosed
US-20150008419-A1 MICROCAVITY OLED DEVICE WITH NARROW BAND PHOSPHORESCENT EMITTERS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2015-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731994-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound CYBA, CYC1, C1S GABRP 4699/4885GABRD 4852/4885GABRA1 4501/4885
US-20230371359-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, MSL1, EML4 GABRP 4802/4885GABRD 4712/4885GABRA1 3976/4885
US-11758803-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device L1CAM, MSL1, EML4 GABRP 4802/4885GABRD 4712/4885GABRA1 3976/4885
US-12018037-B2 Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound ORC3, LEF1, OCIAD1 GABRP 4187/4885GABRD 4034/4885GABRA1 3097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.