SCHEMBL1637403

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15043427	1.00	CYP1A1 (0.40)	CYP1A1CYP1B1GPR84ESR1ESR2
	SCHEMBL1637405	0.96	GPR84 (0.42)	CYP1A1CYP1B1GPR84ESR1ESR2
	SCHEMBL1636390	0.95	GPR84 (0.41)	CYP1A1CYP1B1GPR84ESR1ESR2
	SCHEMBL10226314	0.92	GPR84 (0.40)	CYP1A1CYP1B1GPR84ESR1KDM4E
	SCHEMBL1637857	0.92	GPR84 (0.40)	CYP1A1CYP1B1GPR84ESR1KDM4E
	SCHEMBL1637856	0.92	GPR84 (0.40)	CYP1A1CYP1B1GPR84ESR1KDM4E
	SCHEMBL1636388	0.92	GPR84 (0.40)	CYP1A1CYP1B1GPR84ESR1KDM4E
	SCHEMBL1636384	0.91	PLA2G2A (0.40)	GPR84KDM4EMAPTHPGDTSHR
	SCHEMBL25050915	0.90	ALOX5 (0.40)	GPR84KDM4EMAPTHPGDTSHR
	SCHEMBL25052551	0.90	ALOX5 (0.40)	GPR84KDM4EMAPTHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.