SCHEMBL58375

SCHEMBL58375

Cc1ccc(C(N=C=O)N=C=O)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TRPA1 O75762 2/20 0.34
LMNA P02545 1/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A2 P23975 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CASR P41180 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32
CACNA2D1 P54289 1/20 0.32
CACNA1B Q00975 1/20 0.32
CACNB1 Q02641 1/20 0.32
CYP3A4 P08684 2/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PYCR1 P32322 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8654807 0.80 GABRA1 (0.34) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL4996374 0.79 TRPA1 (0.31) TRPA1CYP3A4
SCHEMBL23527457 0.79 TAS1R3 (0.35) TP53TDP1TRPA1LMNACHRM1
SCHEMBL21259794 0.79 TAS1R3 (0.35) TP53TDP1TRPA1LMNACHRM1
SCHEMBL9276569 0.78 TRPA1 (0.31) TRPA1CYP3A4
SCHEMBL163750 0.76 ESR1 (0.43) LMNACHRM1SLC6A2ADRA1AHTR2B
SCHEMBL5710754 0.74 CYP3A4 (0.32) TRPA1CYP3A4
SCHEMBL9476215 0.74 RAPGEF4 (0.31) TRPA1RAPGEF4CYP3A4
SCHEMBL15063087 0.73 SRC (0.33) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL11682593 0.73 TRPA1 (0.33) TRPA1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105610-B2 Thin-layer-covered golf ball with improved velocity ACUSHNET COMPANY (US) 2006-09-12 US claimed
US-20040198918-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-10-07 US claimed
US-20030114602-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-06-19 US claimed
US-20030096915-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-05-22 US claimed
US-6486261-B1 Thin-layer-covered golf ball with improved velocity ACUSHNET COMPANY 2002-11-26 US claimed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US claimed
US-20260021352-A1 GOLF BALLS WITH INCREASED SHEAR DURABILITY ACUSHNET COMPANY (US) 2026-01-22 US disclosed
US-20250345663-A1 GOLF BALL COMPONENTS FORMED FROM HYDROXYURETHANE COMPOSITIONS ACUSHNET COMPANY (US) 2025-11-13 US disclosed
US-20250345662-A1 GOLF BALL COATINGS FORMED FROM HYDROXYURETHANE COMPOSITIONS ACUSHNET COMPANY (US) 2025-11-13 US disclosed
US-20250303236-A1 HIGH HARDNESS GRADIENT GOLF BALL CORES AND METHODS OF MAKING SAME ACUSHNET COMPANY (US) 2025-10-02 US disclosed
US-12427381-B2 Golf balls with increased shear durability ACUSHNET COMPANY (US) 2025-09-30 US disclosed
US-12377320-B2 Golf ball components formed from hydroxyurethane compositions ACUSHNET COMPANY (US) 2025-08-05 US disclosed
US-12370412-B2 Golf ball coatings formed from hydroxyurethane compositions ACUSHNET COMPANY (US) 2025-07-29 US disclosed
EP-0372295-A2 Aqueous solutions or dispersions for self-cross-linkable binders, process for their manufacture and their use BAYER AG (DE) 1990-06-13 EP disclosed
EP-0324334-A1 Water borne binders, process for their preparation and their use BAYER AG (DE) 1989-07-19 EP disclosed
EP-0218906-A2 Aqueous binder for baking coatings containing a low amount of solvent BAYER AG (DE) 1987-04-22 EP disclosed
US-4383068-A Thixotropic coating agents based on urea adduct of polyamine and monoisocyanate AUGUST MERCKENS NACHFOLGER KOMMANDITGESELLSCHAFT (DE) 1983-05-10 US disclosed
EP-0001304-B1 COATING COMPOSITION HAVING A PROLONGED POT LIFE COMPRISING A PHYSICAL BLEND IN AN ORGANIC SOLVENT OF A POLYHYDROXY COMPOUND AND POLYISOCYANATE AKZO N.V. (NL) 1983-02-23 EP disclosed
EP-0008837-A1 Radiation curable liquid coating composition based on an epoxy terminated compound and a process for coating a substrate with such a composition AKZO N.V. (NL) 1980-03-19 EP disclosed
US-4173682-A ADDUCT OF HYDROXYALKYL ACRYLATE AND POLYISOCYANATE AKZO N.V. (NL) 1979-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021352-A1 GOLF BALLS WITH INCREASED SHEAR DURABILITY EEF2, EEF1A2, GIGYF2 TP53 4172/4885TDP1 2681/4885TRPA1 2421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.