SCHEMBL16385328

SCHEMBL16385328

Fc1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3cccc(-c4ccc(N(c5ccc(F)cc5)c5ccc(-c6ccccc6)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AGXT P21549 1/20 0.43
▸ TAAR1 Q96RJ0 2/20 0.42
▸ ESR2 Q92731 1/20 0.42
▸ BCL2L1 Q07817 1/20 0.41
▸ BAD Q92934 1/20 0.41
▸ FLT3 P36888 1/20 0.41
▸ NR3C1 P04150 1/20 0.41
▸ HTR1A P08908 1/20 0.40
▸ HTR7 P34969 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ESR1 P03372 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ HAO2 Q9NYQ3 1/20 0.40
▸ MGLL Q99685 2/20 0.39
▸ KAT6A Q92794 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28035445 0.92 ALDH1A1 (0.44) TAAR1BCL2L1BADMEN1KMT2A
SCHEMBL17014975 0.92 ALDH1A1 (0.44) TAAR1BCL2L1BADMEN1KMT2A
SCHEMBL17014969 0.92 ALDH1A1 (0.44) TAAR1BCL2L1BADMEN1KMT2A
SCHEMBL17014973 0.92 ALDH1A1 (0.44) TAAR1BCL2L1BADMEN1KMT2A
SCHEMBL10029849 0.92 ALDH1A1 (0.44) TAAR1BCL2L1BADMEN1KMT2A
SCHEMBL19597069 0.91 ACHE (0.43) AGXTTAAR1ESR2BCL2L1BAD
SCHEMBL17014971 0.90 ALDH1A1 (0.48) BCL2L1BADMEN1KMT2AMGLL
SCHEMBL13700810 0.89 MEN1 (0.48) TAAR1MEN1ESR1KMT2AMGLL
SCHEMBL10135847 0.89 MEN1 (0.48) TAAR1MEN1ESR1KMT2AMGLL
SCHEMBL12424018 0.89 MEN1 (0.48) TAAR1MEN1ESR1KMT2AMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 — — EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 — — US disclosed
US-10950797-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-03-16 — — US disclosed
US-10950814-B2 Organic light-emitting diode having long lifespan property SFC CO., LTD. (KR) 2021-03-16 — — US disclosed
US-10892420-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-01-12 — — US disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 — — US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 — — US disclosed
US-20180114916-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-04-26 — — US disclosed
US-20180114916-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-04-26 — — US disclosed
US-9905775-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 — — US disclosed
EP-3163644-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-05-03 — — EP disclosed
US-20170117481-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-04-27 — — US disclosed
US-20170117481-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-04-27 — — US disclosed
WO-2016163276-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-10-13 — — WO disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 — — WO disclosed
WO-2016079944-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-05-26 — — WO disclosed
US-20160118591-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2016-04-28 — — US disclosed
US-20160118591-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2016-04-28 — — US disclosed
WO-2015198563-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2015-12-30 — — WO disclosed
WO-2015004875-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 (JP) 2015-01-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 AGXT 1617/4885TAAR1 450/4885ESR2 130/4885
US-20180114916-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT AGXT 1512/4885TAAR1 471/4885ESR2 102/4885
US-20170117481-A1 ORGANIC ELECTROLUMINESCENT DEVICE KCNN2, KCNN1, SLC7A5 AGXT 2155/4885TAAR1 748/4885ESR2 229/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 AGXT 1698/4885TAAR1 2392/4885ESR2 640/4885
US-10950797-B2 Organic electroluminescent device SLC29A2, SLC29A1, NUDT1 AGXT 1769/4885TAAR1 2594/4885ESR2 584/4885
US-10892420-B2 Organic electroluminescent device SLC7A5, KCNN2, SLC43A1 AGXT 3108/4885TAAR1 629/4885ESR2 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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