SCHEMBL1638569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8797209	0.87	PTGER1 (0.55)	PTGER1RXRARXRBRXRGALDH1A1
	SCHEMBL1642763	0.86	NR1H4 (0.52)	PTGER1RXRARXRBRXRGALDH1A1
	SCHEMBL1667777	0.84	BCAT2 (0.56)	PTGER1RXRARXRBRXRGHTT
	SCHEMBL1639034	0.84	MAOB (0.50)	PTGER1RXRARXRBRXRGALDH1A1
	SCHEMBL1638633	0.84	CCNB2 (0.51)	PTGER1CCNB2CCNE2CDK1CCNB1
	SCHEMBL25431505	0.83	ALDH1A1 (0.56)	PTGER1RXRARXRBRXRGALDH1A1
	SCHEMBL12726013	0.83	SCN9A (0.52)	PTGER1RXRARXRBRXRGL3MBTL1
	SCHEMBL12725979	0.83	ADORA3 (0.50)	PTGER1RXRARXRBRXRGALDH1A1
	SCHEMBL8409192	0.82	LMNA (0.55)	PTGER1RXRARXRBRXRGALDH1A1
	SCHEMBL27894245	0.82	PTGER1 (0.47)	PTGER1RXRARXRBRXRGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.