SCHEMBL16403236

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL701178	0.86	KMT2A (0.54)	HSP90AA1NR4A2KMT2AALDH1A1HPGD
	SCHEMBL8290173	0.81	NR4A2 (0.69)	HSP90AA1NR4A2KMT2AALDH1A1KDM4E
	SCHEMBL18002566	0.81	NR4A2 (0.51)	HSP90AA1NR4A2KMT2AKDM4EMAPT
	SCHEMBL12070632	0.81	KMT2A (0.49)	HSP90AA1NR4A2KMT2AALDH1A1HPGD
	SCHEMBL18002828	0.77	RORC (0.42)	NR4A2KMT2AALDH1A1CYP2C9CYP2C19
	SCHEMBL30593079	0.76	NR4A2 (0.51)	HSP90AA1NR4A2KMT2AALDH1A1HPGD
	SCHEMBL15687165	0.76	HSP90AA1 (0.51)	HSP90AA1NR4A2KMT2AALDH1A1MAPT
	SCHEMBL18002620	0.75	ALDH1A1 (0.47)	KMT2AFFAR4ALDH1A1KDM4EMAPT
	SCHEMBL28069774	0.74	NR4A2 (0.50)	HSP90AA1NR4A2KMT2AALDH1A1KDM4E
	SCHEMBL140918	0.73	ROCK2 (0.47)	KMT2AALDH1A1HPGDCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.