Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403992 | 0.87 | RAB9A (0.60) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL16403918 | 0.87 | NPC1 (0.47) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL16403979 | 0.81 | MGLL (0.48) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL16403966 | 0.80 | LMNA (0.55) | ALDH1A1MAPTLMNAUSP2POLB | |
| SCHEMBL16404152 | 0.79 | ATP4A (0.54) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL16403927 | 0.77 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL16404113 | 0.76 | CCNC (0.55) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL14318296 | 0.75 | HPGD (0.45) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL16403980 | 0.74 | KDM4E (0.44) | ALDH1A1RAB9ANPC1PKMHPGD | |
| SCHEMBL16403981 | 0.74 | RAB9A (0.43) | ALDH1A1RAB9ANPC1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |