Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672456 | 0.98 | CA2 (0.53) | CA2CYP4A11CYP4F2CDK1ALDH5A1 | |
| SCHEMBL2457708 | 0.94 | CA2 (0.50) | CA2CYP4A11CYP4F2CDK1ALDH5A1 | |
| 1,4-Butanediol SCHEMBL29131473 | 0.87 | ALDH5A1 (0.55) | ALDH5A1ABATALDH1A1LMNAMAPT | |
| SCHEMBL77237 | 0.85 | CA2 (0.52) | CA2CYP4A11CYP4F2ALDH5A1ABAT | |
| SCHEMBL15452989 | 0.84 | ALDH1A1 (0.47) | CDK1ALDH5A1ABATALDH1A1LMNA | |
| SCHEMBL18643996 | 0.82 | HCAR2 (0.46) | CA2CYP4A11CYP4F2CDK1BCHE | |
| SCHEMBL242504 | 0.82 | CA2 (0.61) | CA2CYP4A11CYP4F2BCHEALDH1A1 | |
| SCHEMBL17278365 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2CYP2A6 | |
| SCHEMBL23837668 | 0.79 | CA2 (0.63) | CA2CYP4A11CYP4F2BCHEALDH1A1 | |
| SCHEMBL4195590 | 0.79 | CA2 (0.63) | CA2CYP4A11CYP4F2BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12286426-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | Université de Montréal (CA) | 2025-04-29 | — | — | US | disclosed |
| EP-3704111-B1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | UNIV MONTREAL (CA) | 2024-10-09 | — | — | EP | disclosed |
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |
| US-20230357221-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | UNIV MONTREAL (CA) | 2023-11-09 | — | — | US | disclosed |
| US-20230357221-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | UNIV MONTREAL (CA) | 2023-11-09 | — | — | US | disclosed |
| US-20230357221-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | UNIV MONTREAL (CA) | 2023-11-09 | — | — | US | disclosed |
| US-11760754-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | Université de Montréal (CA) | 2023-09-19 | — | — | US | disclosed |
| US-11760754-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | Université de Montréal (CA) | 2023-09-19 | — | — | US | disclosed |
| US-11760754-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | Université de Montréal (CA) | 2023-09-19 | — | — | US | disclosed |
| US-20210387980-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | Université de Montréal (CA) | 2021-12-16 | — | — | US | disclosed |
| US-20210387980-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | Université de Montréal (CA) | 2021-12-16 | — | — | US | disclosed |
| CN-111886234-A | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2020-11-03 | — | — | CN | disclosed |
| EP-3704111-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | Université de Montréal (CA) | 2020-09-09 | — | — | EP | disclosed |
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | DIC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | DIC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
| US-9278989-B2 | Sugar-derived gelator | KYUSHU UNIVERSITY (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20150025157-A1 | NOVEL SUGAR-DERIVED GELATOR | INSTITUTE OF SYSTEMS, INFORMATION TECHNOLOGIES AND NANOTECHNOLOGIES (JP) | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357221-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | IDH2, TFAM, IDH1 | CA2 425/4885CYP4A11 2221/4885CYP4F2 1015/4885 |
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | SMC4, MAP1LC3C, ZW10 | CA2 4332/4885CYP4A11 1945/4885CYP4F2 3191/4885 |
| US-20150025157-A1 | NOVEL SUGAR-DERIVED GELATOR | UGGT1, GCK, B3GAT3 | CA2 3835/4885CYP4A11 1938/4885CYP4F2 2380/4885 |
| US-12286426-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | IDH2, TFAM, IDH1 | CA2 425/4885CYP4A11 2221/4885CYP4F2 1015/4885 |
| US-20210387980-A1 | HETEROCYCLIC MITOCHONDRIAL ACTIVITY INHIBITORS AND USES THEREOF | IDH2, TFAM, NUTF2 | CA2 473/4885CYP4A11 2205/4885CYP4F2 807/4885 |
| US-11760754-B2 | Heterocyclic mitochondrial activity inhibitors and uses thereof | IDH2, TFAM, NUTF2 | CA2 473/4885CYP4A11 2205/4885CYP4F2 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.