Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976214 | 0.97 | STAT3 (0.48) | STAT3STAT1 | |
| SCHEMBL1290623 | 0.85 | STAT3 (0.56) | STAT3STAT1 | |
| SCHEMBL29738339 | 0.85 | STAT3 (0.58) | STAT3STAT1 | |
| SCHEMBL31127549 | 0.84 | STAT3 (0.57) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL5596534 | 0.83 | STAT3 (0.53) | STAT3STAT1 | |
| SCHEMBL1978627 | 0.82 | STAT3 (0.56) | STAT3STAT1 | |
| SCHEMBL30426808 | 0.82 | STAT3 (0.56) | STAT3STAT1 | |
| SCHEMBL4258776 | 0.82 | STAT3 (0.43) | STAT3STAT1 | |
| SCHEMBL16594302 | 0.80 | STAT3 (0.71) | STAT3STAT1 | |
| SCHEMBL19206150 | 0.77 | STAT3 (0.53) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201201-B1 | SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2022-01-26 | — | — | EP | disclosed |
| US-10456375-B2 | Specifically meso-substituted porphyrins and chlorins for photodynamic therapy | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2019-10-29 | — | — | US | disclosed |
| US-10035806-B2 | Derivatized corroles and metallocorroles and their use as imaging and therapeutic agents | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180036284-A1 | SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2018-02-08 | — | — | US | disclosed |
| EP-3201201-A1 | SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY | biolitec unternehmensbeteiligungs II AG (AT) | 2017-08-09 | — | — | EP | disclosed |
| US-20170096434-A1 | DERIVATIZED CORROLES AND METALLOCORROLES AND THEIR USE AS IMAGING AND THERAPEUTIC AGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-04-06 | — | — | US | disclosed |
| US-9572816-B2 | Method of treatment of disease | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2017-02-21 | — | — | US | disclosed |
| WO-2016051361-A1 | SPECIFICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2016-04-07 | — | — | WO | disclosed |
| US-20150290214-A1 | METHOD OF TREATMENT OF DISEASE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2015-10-15 | — | — | US | disclosed |
| EP-2911662-A1 | METHOD OF TREATMENT OF DISEASE | Technion Research and Development Foundation Ltd. (IL) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014064697-A1 | METHOD OF TREATMENT OF DISEASE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2014-05-01 | — | — | WO | disclosed |
| US-20140045809-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2014-02-13 | — | — | US | disclosed |
| EP-2244701-B1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RES & DEV FOUNDATION (IL) | 2012-05-09 | — | — | EP | disclosed |
| US-20110098262-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPEMENT FOUNDATION, LTD. (IL) | 2011-04-28 | — | — | US | disclosed |
| EP-2244701-A2 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | Technion Research and Development Foundation, Ltd. (IL) | 2010-11-03 | — | — | EP | disclosed |
| EP-2179006-A1 | INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE | Karlsruher Institut für Technologie (DE) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009100800-A1 | INORGANIC-ORGANIC COMPOSITE FLUORESCENT SUBSTANCE | UNIVERSITÄT KARLSRUHE (TH) (DE) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009095923-A2 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD (IL) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098262-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | IAPP, CASP3, SOD1 | STAT3 1610/4885STAT1 2736/4885 |
| US-20150290214-A1 | METHOD OF TREATMENT OF DISEASE | REN, PKD1, IAPP | STAT3 1233/4885STAT1 1785/4885 |
| US-10035806-B2 | Derivatized corroles and metallocorroles and their use as imaging and therapeutic agents | MGMT, MEN1, MB | STAT3 2916/4885STAT1 4005/4885 |
| US-20170096434-A1 | DERIVATIZED CORROLES AND METALLOCORROLES AND THEIR USE AS IMAGING AND THERAPEUTIC AGENTS | MGMT, MEN1, MB | STAT3 2916/4885STAT1 4005/4885 |
| US-20140045809-A1 | CORROLES FOR NEUROPROTECTION AND NEURORESCUE | IAPP, CASP3, SOD1 | STAT3 1610/4885STAT1 2736/4885 |
| US-20180036284-A1 | SPECIFICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PHOTODYNAMIC THERAPY | DHPS, DDT, PPOX | STAT3 998/4885STAT1 1838/4885 |
| US-10456375-B2 | Specifically meso-substituted porphyrins and chlorins for photodynamic therapy | DHPS, DDT, PPOX | STAT3 998/4885STAT1 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.