Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31162575 | 1.00 | SYK (0.51) | SYKITKL3MBTL1HDAC4KMT2A | |
| SCHEMBL4881318 | 0.84 | KMT2A (0.42) | SYKITKL3MBTL1HDAC4KMT2A | |
| SCHEMBL23772048 | 0.82 | SYK (0.41) | SYKL3MBTL1KMT2AKDM4EMEN1 | |
| SCHEMBL2138274 | 0.81 | HDAC4 (0.56) | SYKL3MBTL1HDAC4KMT2AKDM4E | |
| SCHEMBL25817273 | 0.78 | L3MBTL1 (0.50) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL25054811 | 0.75 | SMN1; SMN2 (0.39) | L3MBTL1KMT2AKDM4EMEN1NPC1 | |
| SCHEMBL21016714 | 0.74 | ITK (0.52) | ITKKMT2AKDM4EMEN1MAPT | |
| SCHEMBL32526767 | 0.74 | L3MBTL1 (0.50) | ITKL3MBTL1KMT2AKDM4EMEN1 | |
| SCHEMBL832407 | 0.74 | L3MBTL1 (0.50) | ITKL3MBTL1KMT2AKDM4EMEN1 | |
| SCHEMBL15745464 | 0.73 | ADORA1 (0.53) | L3MBTL1KMT2AKDM4EMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917900-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-11917900-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230192669-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192669-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-11588115-B2 | Nitrogen-containing compound, organic electroluminescent device and electronic apparatus | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2023-02-21 | — | — | US | disclosed |
| US-20220223800-A1 | ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| US-20210249602-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-08-12 | — | — | US | disclosed |
| US-10538533-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2020-01-21 | — | — | US | disclosed |
| US-20180118762-A1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | US | disclosed |
| US-20180118762-A1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-03 | — | — | US | disclosed |
| US-9802960-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-9802960-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-9751854-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-09-05 | — | — | US | disclosed |
| US-9751854-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-09-05 | — | — | US | disclosed |
| US-20170073326-A1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20170073326-A1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-03-16 | — | — | US | disclosed |
| CN-103193717-B | M-phenyl bipyrimidine compound, and synthesis method and application thereof | 南京工业大学 | 2017-01-25 | — | — | CN | disclosed |
| US-20150225422-A1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-08-13 | — | — | US | disclosed |
| US-20150031709-A1 | Heteroaryl Compounds and Methods of Use Thereof | SUNOVION PHARMACEUTICALS, INC. (US) | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192669-A1 | COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS | ACHE, OR51E2, L1CAM | SYK 2060/4885ITK 2686/4885L3MBTL1 1994/4885 |
| US-20150031709-A1 | Heteroaryl Compounds and Methods of Use Thereof | COMT, GRIN2C, TPMT | SYK 3466/4885ITK 2900/4885L3MBTL1 3393/4885 |
| US-20210249602-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OTC, OSBP, OCIAD2 | SYK 3260/4885ITK 2384/4885L3MBTL1 1605/4885 |
| US-20220223800-A1 | ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE | OCIAD2, EMC2, OCIAD1 | SYK 2414/4885ITK 2080/4885L3MBTL1 3894/4885 |
| US-11588115-B2 | Nitrogen-containing compound, organic electroluminescent device and electronic apparatus | NCL, NCLN, NNMT | SYK 1754/4885ITK 1479/4885L3MBTL1 688/4885 |
| US-20180118762-A1 | HETEROARYLS AND USES THEREOF | VPS35, VPS4B, VPS26B | SYK 2690/4885ITK 4728/4885L3MBTL1 171/4885 |
| US-10538533-B2 | Heteroaryls and uses thereof | VPS35, VPS4B, VPS26B | SYK 2690/4885ITK 4728/4885L3MBTL1 171/4885 |
| US-11917900-B2 | Organic electroluminescent materials and devices | OTC, OSBP, OCIAD2 | SYK 3260/4885ITK 2384/4885L3MBTL1 1605/4885 |
| US-20150225422-A1 | HETEROARYLS AND USES THEREOF | VPS35, VPS4B, VPS26B | SYK 2690/4885ITK 4728/4885L3MBTL1 171/4885 |
| US-20170073326-A1 | HETEROARYLS AND USES THEREOF | VPS35, VPS4B, VPS26B | SYK 2690/4885ITK 4728/4885L3MBTL1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.