Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GAPDH | P04406 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12687656 | 0.85 | ACHE (0.35) | ALDH1A1 | |
| SCHEMBL12687864 | 0.81 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12687654 | 0.81 | BCHE (0.30) | — | |
| SCHEMBL12687865 | 0.80 | MEN1 (0.32) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL1652645 | 0.75 | NPC1 (0.31) | NPC1RAB9ATP53 | |
| SCHEMBL16433674 | 0.75 | DAO (0.32) | DAOTP53 | |
| SCHEMBL8744701 | 0.72 | VDR (0.32) | MEN1KMT2A | |
| SCHEMBL12688024 | 0.72 | MMP1 (0.30) | — | |
| SCHEMBL8744823 | 0.70 | TAS1R3 (0.32) | ALDH1A1MEN1KMT2AGAPDHPOLB | |
| SCHEMBL12239229 | 0.69 | DAO (0.34) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661424-B1 | 4-(ORTHO-SUBSTITUTED-PHENYL)-5-OXO-2,5-DIHYDRO-1H-PYRROLE COMPOUNDS AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-12 | — | — | EP | disclosed |
| US-8946453-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-8946453-B2 | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-20140011845-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-09 | — | — | US | disclosed |
| US-20140011845-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011845-A1 | CHEMICAL COMPOUNDS | CYP1B1, CYP1A1, NQO1 | ALDH1A1 30/4885MAPT 3852/4885MAPK1 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.