Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648444 | 0.76 | PBRM1 (0.32) | MEN1KMT2APBRM1 | |
| SCHEMBL12687656 | 0.72 | ACHE (0.35) | — | |
| SCHEMBL16433665 | 0.72 | ALDH1A1 (0.32) | MEN1KMT2A | |
| SCHEMBL12687654 | 0.70 | BCHE (0.30) | — | |
| SCHEMBL8744823 | 0.70 | TAS1R3 (0.32) | KDM4EMEN1KMT2APBRM1 | |
| SCHEMBL2867325 | 0.68 | MEN1 (0.41) | VDRMEN1KMT2AGAAHTT | |
| SCHEMBL163425 | 0.68 | MEN1 (0.41) | VDRMEN1KMT2AGAAHTT | |
| SCHEMBL12687865 | 0.67 | MEN1 (0.32) | KDM4EMEN1KMT2AHTT | |
| SCHEMBL20392736 | 0.67 | — | — | |
| SCHEMBL8744726 | 0.67 | USP2 (0.36) | KDM4EMEN1KMT2APBRM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |