Water

Water

SCHEMBL16443

O.O.O.[Cl-].[Cl-].[Cl-].[Rh+3]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL383055 1.00
Water SCHEMBL5353098 1.00
Water SCHEMBL8911037 1.00
Water SCHEMBL8063198 1.00
Hydrochloric Acid SCHEMBL106286 0.82
Water SCHEMBL23461833 0.67
Water SCHEMBL23631871 0.67
Water SCHEMBL20562889 0.67
Water SCHEMBL25334174 0.67
Water SCHEMBL21379772 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 846 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119951533-A Layered nickel-aluminum bimetallic oxide supported bimetallic active component catalyst and preparation method thereof, and method for preparing primary amine by reductive amination of biomass carbonyl compound 陕西科技大学 2025-05-09 CN claimed
CN-115700297-B Electrode material for synthesizing nitrous oxide and preparation method and application thereof 万华化学集团股份有限公司 2025-04-01 CN claimed
CN-119703048-A Multi-element metal nano-sheet, preparation method and application thereof 华能伊敏煤电有限责任公司 2025-03-28 CN claimed
US-20250083137-A1 SUPPORTED HYDROFORMYLATION CATALYST AND PREPARATION METHOD THEREOF, AND METHOD FOR SYNTHESIZING 4-ACETYLOXY-2-METHYL-2-BUTENAL SHAOXING UNIVERSITY (CN) 2025-03-13 US claimed
CN-119114131-A Cobalt-rhodium doped nitriding active carbon supported composite catalyst and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2024-12-13 CN claimed
CN-118988303-A Hydrothermally stable core-shell structure three-way catalyst and preparation method and application thereof 宁波诺丁汉大学 2024-11-22 CN claimed
CN-118751265-A Isononaldehyde catalyst for diisobutylene hydroformylation and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2024-10-11 CN claimed
CN-118724689-A Method for preparing glycolaldehyde by bridged catalytic formylating formaldehyde 天津大学 2024-10-01 CN claimed
CN-118702863-A Preparation of biphosphine polymer-embedded rhodium-based catalyst and its use in CO2Use of hydroformylation of olefins as a source of carbonyl 中国科学院兰州化学物理研究所 2024-09-27 CN claimed
CN-118616057-A High-entropy alloy hydrotalcite-like oxide composite material, and preparation method and application thereof 安徽师范大学 2024-09-10 CN claimed
US-4500458-A CATALYST FROM RHODIUM SALT OR A COMPLEX WITH A HYDRAZINE PLURICHEMIE ANSTALT (LI) 1985-02-19 US claimed
EP-0126501-A2 Process for the preparation of alpha-haloalkyl esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-11-28 EP claimed
EP-0031606-B1 PROCESS FOR THE CO-PRODUCTION OF CARBOXYLIC ACIDS AND CARBOXYLIC ACID ESTERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-08-24 EP claimed
EP-0085204-A1 Process for the co-production of carboxylic acids and carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-08-10 EP claimed
EP-0083121-A1 Process for the co-production of carboxylic acids and carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-07-06 EP claimed
EP-0075337-A1 Process for the co-production of carboxylic acids and carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-03-30 EP claimed
EP-0075335-A1 Process for the co-production of carboxylic acids and carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-03-30 EP claimed
EP-0072055-A1 Process for the co-production of carboxylic acids and carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-02-16 EP claimed
US-4356126-A IN PRESENCE OF GROUP VIII COMPOUND AND PENTACHLOROBENZENETHIOL SHELL OIL COMPANY (US) 1982-10-26 US claimed
EP-0031606-A1 Process for the co-production of carboxylic acids and carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-07-08 EP claimed