Water

Water

SCHEMBL8911037

O.O.O.O.O.O.[Cl-].[Cl-].[Cl-].[Rh+3]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL383055 1.00
Water SCHEMBL5353098 1.00
Water SCHEMBL8063198 1.00
Water SCHEMBL16443 1.00
Hydrochloric Acid SCHEMBL106286 0.82
Water SCHEMBL23461833 0.67
Water SCHEMBL23631871 0.67
Water SCHEMBL20562889 0.67
Water SCHEMBL25334174 0.67
Water SCHEMBL21379772 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113426487-B Catalyst for preparing propionaldehyde by ethylene hydroformylation and preparation method thereof 天津大学 2022-12-23 CN claimed
CN-113426487-A Catalyst for preparing propionaldehyde by ethylene hydroformylation and preparation method thereof 天津大学 2021-09-24 CN claimed
CN-113426487-B Catalyst for preparing propionaldehyde by ethylene hydroformylation and preparation method thereof 天津大学 2022-12-23 CN disclosed
CN-113426487-B Catalyst for preparing propionaldehyde by ethylene hydroformylation and preparation method thereof 天津大学 2022-12-23 CN disclosed
CN-113426487-A Catalyst for preparing propionaldehyde by ethylene hydroformylation and preparation method thereof 天津大学 2021-09-24 CN disclosed
CN-113426487-A Catalyst for preparing propionaldehyde by ethylene hydroformylation and preparation method thereof 天津大学 2021-09-24 CN disclosed
US-5665471-A Fiber treatment compositions and methods for the preparation thereof DOW CORNING CORPORATION (US) 1997-09-09 US disclosed
US-5567347-A SMOOTHNESS, SOFTNESS, WATERPROOFING DOW CORNING CORPORATION (US) 1996-10-22 US disclosed
US-5527476-A RHODIUM CATALYST FOR CROSSLINKING METHYLHYDROGENSILOXANES IN TREATING FIBERS OR FABRICS DOW CORNING CORPORATION (US) 1996-06-18 US disclosed
US-5518775-A IMPROVED SLICKNESS, COMPRESSION RESISTANCE, WATER REPELLENCY, CROSSLINKING MIXTURE OF SILICONES AND UNSATURATED ESTERS DOW CORNING CORPORATION (US) 1996-05-21 US disclosed
US-5514418-A UNSATURATED ACETATE, ALKYLHYDROGENSILOXANE, METAL CATALYST, TEXTILES DOW CORNING CORPORATION (US) 1996-05-07 US disclosed
US-5464801-A Crosslinking polysiloxanes DOW CORNING CORPORATION (US) 1995-11-07 US disclosed
EP-0661399-A1 Catalyst compositions and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-07-05 EP disclosed
EP-0661400-A1 Fiber treatment compositions and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-07-05 EP disclosed
EP-0661398-A1 Fiber treatment compositions containing organofunctional siloxanes and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-07-05 EP disclosed
US-5409620-A Fiber treatment compositions containing organofunctional siloxanes and methods for the preparation thereof DOW CORNING CORPORATION (US) 1995-04-25 US disclosed