Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 3/20 | 0.39 |
| ▸ | SKP1 | P63208 | 3/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516589 | 0.90 | DGAT1 (0.45) | DGAT1MAPTALDH1A1TP53LMNA | |
| SCHEMBL12516585 | 0.88 | DGAT1 (0.44) | DGAT1MAPTALDH1A1TP53LMNA | |
| SCHEMBL14665458 | 0.86 | DGAT1 (0.43) | DGAT1MAPTALDH1A1TP53MEN1 | |
| SCHEMBL16449165 | 0.82 | OPRK1 (0.52) | — | |
| SCHEMBL12516588 | 0.80 | CXCR3 (0.52) | DGAT1MAPTTP53LMNAMEN1 | |
| SCHEMBL16449164 | 0.80 | USP14 (0.46) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL16449190 | 0.80 | GPR119 (0.39) | DGAT1MAPTALDH1A1TP53LMNA | |
| SCHEMBL22657728 | 0.76 | ATM (0.51) | DGAT1MAPTALDH1A1TP53LMNA | |
| SCHEMBL10380233 | 0.76 | FFAR4 (0.41) | DGAT1FFAR4 | |
| SCHEMBL12813874 | 0.76 | ALDH1A1 (0.55) | DGAT1MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952004-B2 | CXCR3 receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-10 | — | — | US | disclosed |