SCHEMBL1645559

SCHEMBL1645559

CC(CCCO)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
HTR2A P28223 1/20 0.47
HRH1 P35367 1/20 0.47
KCNH2 Q12809 1/20 0.47
LMNA P02545 7/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPT P10636 4/20 0.45
ATM Q13315 2/20 0.45
NPC1 O15118 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
MDM2 Q00987 1/20 0.43
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5252788 0.95 PGR (0.46) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL8471027 0.93 PGR (0.45) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL8473579 0.93 PGR (0.45) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL11170402 0.90 PGR (0.52) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL8733899 0.85 PGR (0.51) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL4994418 0.85 PGR (0.51) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL6424289 0.84 CES2 (0.50) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL5252785 0.84 PGR (0.46) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL24896949 0.82 HDAC1 (0.53) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL6684015 0.82 CES2 (0.51) PGRADRA2AADRA2BHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9757493-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2017-09-12 US claimed
US-20160250376-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME TUTOGEN MEDICAL, INC. 2016-09-01 US claimed
EP-2192886-A2 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME Pioneer Surgical Technology, Inc. (US) 2010-06-09 EP claimed
US-20090270527-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME ANGSTROM MEDICA (US) 2009-10-29 US claimed
WO-2009029734-A2 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME PIONEER SURGICAL TECHNOLOGY, INC. (US) 2009-03-05 WO claimed
US-20250083136-A1 METHODS AND SYSTEMS FOR MODIFYING SELECTIVITY IN CATALYTIC REACTIONS U.S. DEPARTMENT OF ENERGY 2025-03-13 US disclosed
CN-111253583-B Dilatant hybrid dynamic polymer and dilatant realization method thereof 厦门天策材料科技有限公司 2023-05-16 CN disclosed
CN-108329265-B Imidazole ion-containing photocuring monomer and application thereof in self-repairing photocuring material 北京化工大学 2020-11-03 CN disclosed
US-10799610-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2020-10-13 US disclosed
CN-111253583-A Dilatancy hybrid dynamic polymer and method for realizing dilatancy thereof 翁秋梅 2020-06-09 CN disclosed
CN-111171329-A Plastic dilatancy polymer and method for realizing dilatancy thereof 翁秋梅 2020-05-19 CN disclosed
US-10413632-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2019-09-17 US disclosed
EP-1922052-A2 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME Angstrom Medica, Inc. (US) 2008-05-21 EP disclosed
US-20070293948-A1 Bioactive Spinal Implants and Method of Manufacture Thereof VITA SPECIAL PURPOSE CORPORATION 2007-12-20 US disclosed
US-7238203-B2 Bioactive spinal implants and method of manufacture thereof VITA SPECIAL PURPOSE CORPORATION (US) 2007-07-03 US disclosed
WO-2007019461-A2 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME ANGSTROM MEDICA, INC. (US) 2007-02-15 WO disclosed
US-20070032568-A1 Cement products and methods of making and using the same ANGSTROM MEDICA (US) 2007-02-08 US disclosed
US-6987136-B2 Bioactive spinal implant material and method of manufacture thereof VITA SPECIAL PURPOSE CORPORATION (US) 2006-01-17 US disclosed
US-20030125739-A1 Bioactive spinal implants and method of manufacture thereof VITA SPECIAL PURPOSE CORP. 2003-07-03 US disclosed
US-20030087984-A1 Bioactive spinal implant material and method of manufacture thereof VITA SPECIAL PURPOSE CORP. 2003-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250083136-A1 METHODS AND SYSTEMS FOR MODIFYING SELECTIVITY IN CATALYTIC REACTIONS HMBS, UNG, MPG PGR 2649/4885ADRA2A 3435/4885ADRA2B 3558/4885
US-20070032568-A1 Cement products and methods of making and using the same BMP2, ETF1, EPHX2 PGR 2357/4885ADRA2A 4214/4885ADRA2B 4229/4885
US-20160250376-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT PGR 3040/4885ADRA2A 4698/4885ADRA2B 4716/4885
US-10799610-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT PGR 3040/4885ADRA2A 4698/4885ADRA2B 4716/4885
US-10413632-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT PGR 3040/4885ADRA2A 4698/4885ADRA2B 4716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.