Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16458693 | 0.91 | OPRL1 (0.34) | OPRL1OPRM1OPRD1OPRK1HTR2A | |
| Hydrochloric Acid SCHEMBL16459338 | 0.87 | PSEN1 (0.33) | OPRL1OPRM1OPRD1OPRK1CYP19A1 | |
| Hydrochloric Acid SCHEMBL16458218 | 0.85 | LMNA (0.32) | OPRL1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL16458985 | 0.83 | CNR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL16459181 | 0.78 | OPRM1 (0.32) | OPRL1OPRM1OPRD1OPRK1CYP19A1 | |
| Hydrochloric Acid SCHEMBL16459516 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL16458040 | 0.71 | SIGMAR1 (0.33) | OPRL1OPRM1OPRD1OPRK1HTR2A | |
| Hydrochloric Acid SCHEMBL10317637 | 0.71 | CES2 (0.33) | OPRL1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL16459103 | 0.71 | OPRM1 (0.33) | OPRL1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL16458211 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | AP2A1, AP1M1, ME1 | OPRL1 4521/4885OPRM1 2129/4885OPRD1 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.