SCHEMBL16467792

SCHEMBL16467792

COS(=O)(=O)c1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
CTPS1 P17812 1/20 0.42
ALPL P05186 1/20 0.40
ALPI P09923 1/20 0.40
TSHR P16473 2/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
PGR P06401 1/20 0.37
GUSB P08236 1/20 0.35
KMT2A Q03164 2/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA14 Q9ULX7 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9510017 0.79 CTPS1 (0.33) CTPS1TSHRGLAPOLBTRPV4
SCHEMBL16467798 0.79 SMN1; SMN2 (0.40) L3MBTL1POLBPGRCA1CA2
SCHEMBL16467791 0.77 L3MBTL1 (0.40) L3MBTL1CTPS1ALPLALPIPGR
SCHEMBL5318058 0.77 ALDH1A1 (0.49) L3MBTL1ALPLALPITSHRPOLB
SCHEMBL13290774 0.77 THRB (0.35) ALPLTSHRGLAKMT2ACA1
SCHEMBL13290923 0.77 TRPV4 (0.50) TSHRPOLBKMT2ATRPV4ALDH1A1
SCHEMBL6114769 0.76 L3MBTL1 (0.39) L3MBTL1CTPS1ALPLALPITSHR
SCHEMBL9950188 0.74 TRPV4 (0.38) L3MBTL1ALPLTSHRPOLBCA1
SCHEMBL27558723 0.74 L3MBTL1 (0.38) L3MBTL1CTPS1ALPLALPIPGR
SCHEMBL15353058 0.74 KDM4E (0.42) TSHRPGRKMT2AMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES CBR3, CYCS, CBR1 L3MBTL1 238/4885CTPS1 3125/4885ALPL 4619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.