SCHEMBL16481995

SCHEMBL16481995

COC(=O)c1cccc(-c2ccc(-n3c4ccncc4c4cnccc43)cc2C)c1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.50
DGAT2 Q96PD7 12/20 0.49
NEK1 Q96PY6 4/20 0.45
AXL P30530 1/20 0.43
ROCK2 O75116 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16481983 0.88 AKR1C3 (0.47)
SCHEMBL16482132 0.81 MGAT2 (0.52) DGAT2
SCHEMBL16482337 0.81 RPS6KA3 (0.41)
SCHEMBL16482012 0.79 MEN1 (0.38)
SCHEMBL16482061 0.78 PRKCI (0.44)
SCHEMBL13098376 0.78 AOC3 (0.36)
SCHEMBL5028258 0.76 CYP19A1 (0.38)
SCHEMBL10018490 0.76 HTT (0.35)
SCHEMBL10018491 0.75 HTR7 (0.37) DGAT2
SCHEMBL261774 0.75 MAOA (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus MERCK PATENT GMBH (DE) 2020-12-08 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2018-07-26 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160372683-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, AND LIGHT-EMITTING COMPOSITION Konica Minolta, Inc. (JP) 2016-12-22 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20160197282-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHT EMITTING DEVICE, LIGHTING DEVICE, DISPLAY DEVICE AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2016-07-07 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
WO-2014057971-A1 ELECTROLUMINESCENCE ELEMENT コニカミノルタ株式会社 (JP) 2014-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212157-A1 ORGANIC ELECTROLUMINESCENT DEVICE, THIN LUMINOUS FILM, DISPLAY APPARATUS, AND LIGHTING APPARATUS LPO, L1CAM, EML4 SLC2A1 3137/4885DGAT2 2353/4885NEK1 1346/4885
US-10862048-B2 Organic electroluminescent device, thin luminous film, display apparatus, and lighting apparatus LPO, L1CAM, EML4 SLC2A1 3137/4885DGAT2 2353/4885NEK1 1346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.