Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499203 | 0.82 | L3MBTL1 (0.46) | MAPTKMT2ALMNAHPGDTDP1 | |
| SCHEMBL18692826 | 0.74 | KMT2A (0.57) | MAPTKMT2AGAAPDE4DTP53 | |
| SCHEMBL3299372 | 0.72 | KMT2A (0.68) | MAPTKMT2AGAAPDE4DTP53 | |
| SCHEMBL7268 | 0.72 | KMT2A (0.68) | MAPTKMT2AGAAPDE4DTP53 | |
| SCHEMBL6123645 | 0.72 | ALDH1A1 (0.57) | MAPTGAAPDE4DTP53HPGD | |
| SCHEMBL28625965 | 0.71 | KMT2A (0.67) | MAPTKMT2AGAAPDE4DTP53 | |
| SCHEMBL4981925 | 0.70 | LMNA (0.56) | KMT2AGAAPDE4DTP53LMNA | |
| SCHEMBL22896893 | 0.70 | KMT2A (0.65) | MAPTKMT2AGAAPDE4DTP53 | |
| SCHEMBL10374929 | 0.70 | TP53 (0.75) | MAPTPDE4DTP53HPGDCYP1A2 | |
| SCHEMBL13853259 | 0.70 | CYP1A2 (0.50) | MAPTKMT2AGAAGABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |