Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | NEK2 | P51955 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498311 | 0.82 | CYP2C19 (0.50) | L3MBTL1RPA1PPP1CAALDH1A1SMN1; SMN2 | |
| SCHEMBL16498386 | 0.82 | MAPT (0.50) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL16498309 | 0.76 | KEAP1 (0.43) | L3MBTL1RPA1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11730545 | 0.75 | RAB9A (0.42) | L3MBTL1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL16512866 | 0.73 | PTGER1 (0.46) | L3MBTL1RPA1PPP1CAALDH1A1SMN1; SMN2 | |
| SCHEMBL16512870 | 0.73 | BCAT1 (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2ESR2 | |
| SCHEMBL19465578 | 0.72 | KDM4E (0.60) | L3MBTL1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL16512869 | 0.69 | ESR2 (0.46) | L3MBTL1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL924712 | 0.67 | RPA1 (0.56) | L3MBTL1RPA1PPP1CAALDH1A1SMN1; SMN2 | |
| SCHEMBL6681735 | 0.67 | HPGD (0.69) | ALDH1A1HPGDSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |