SCHEMBL16504352

SCHEMBL16504352

ClCCCNCCNCCCCl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 2/20 0.44
TSHR P16473 5/20 0.43
TDP1 Q9NUW8 4/20 0.43
ALDH1A1 P00352 4/20 0.43
CA12 O43570 5/20 0.41
CA6 P23280 5/20 0.41
CA7 P43166 5/20 0.41
CA9 Q16790 5/20 0.41
CA14 Q9ULX7 5/20 0.41
CA5B Q9Y2D0 5/20 0.41
CA2 P00918 4/20 0.41
CA4 P22748 4/20 0.41
CA5A P35218 4/20 0.41
LMNA P02545 3/20 0.41
CA3 P07451 3/20 0.41
ALOX15 P16050 3/20 0.41
CA1 P00915 2/20 0.41
TP53 P04637 1/20 0.41
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9771596 0.96 KDM4E (0.44) CASP2TSHRTDP1ALDH1A1CA12
SCHEMBL2000125 0.96
SCHEMBL3207850 0.89
Hydrochloric Acid SCHEMBL7038936 0.86
SCHEMBL25154093 0.85 TSHR (0.55) CASP2TSHRTDP1ALDH1A1CA12
SCHEMBL22505071 0.83
SCHEMBL2709324 0.81
SCHEMBL22566437 0.81
SCHEMBL274740 0.81
SCHEMBL14871705 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116211887-A Composition for treating acid-base imbalance 特里赛达公司 2023-06-06 CN claimed
US-11197887-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2021-12-14 US claimed
US-20210205351-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS RENIBUS THERAPEUTICS, INC. 2021-07-08 US claimed
EP-3831395-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS Tricida Inc. (US) 2021-06-09 EP claimed
EP-3593808-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2020-12-09 EP claimed
EP-3578185-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2020-08-05 EP claimed
EP-3229816-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2020-02-05 EP claimed
US-20190209607-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS TRICIDA, INC. 2019-07-11 US claimed
EP-3287133-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2019-04-17 EP claimed
EP-3287133-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION Tricida Inc. (US) 2018-02-28 EP claimed
EP-3812761-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENOSIS INC (US) 2025-12-24 EP disclosed
US-20250222021-A1 METHOD OF TREATING ACID-BASE DISORDERS RENIBUS THERAPEUTICS, INC. 2025-07-10 US disclosed
US-20250025494-A1 COMPOSITIONS FOR AND METHOD OF TREATING ACID-BASE DISORDERS RENIBUS THERAPEUTICS, INC. 2025-01-23 US disclosed
US-20250009785-A1 HCL-BINDING COMPOSITIONS FOR AND METHODS OF TREATING ACID-BASE DISORDERS RENIBUS THERAPEUTICS, INC. 2025-01-09 US disclosed
US-11992501-B2 Compositions for and methods of treating acid-base disorders RENOSIS, INC. (US) 2024-05-28 US disclosed
WO-2017193050-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS TRICIDA, INC. (US) 2017-11-09 WO disclosed
EP-3003327-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION TRICIDA INC (US) 2017-08-09 EP disclosed
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2016-03-17 US disclosed
US-9205107-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2015-12-08 US disclosed
US-20150056451-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2015-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992501-B2 Compositions for and methods of treating acid-base disorders SLC10A2, SLC10A1, SLC26A3 CASP2 4329/4885TSHR 2197/4885TDP1 2675/4885
US-20150056451-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 CASP2 4532/4885TSHR 1639/4885TDP1 3385/4885
US-20250222021-A1 METHOD OF TREATING ACID-BASE DISORDERS SLC10A2, SLC10A1, SI CASP2 4108/4885TSHR 1626/4885TDP1 2189/4885
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 CASP2 4532/4885TSHR 1639/4885TDP1 3385/4885
US-20250009785-A1 HCL-BINDING COMPOSITIONS FOR AND METHODS OF TREATING ACID-BASE DISORDERS SLC10A2, SLC10A1, SLC7A1 CASP2 4634/4885TSHR 1667/4885TDP1 2827/4885
US-20210205351-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS SLC10A2, SLC10A1, SLC26A3 CASP2 4421/4885TSHR 2261/4885TDP1 2434/4885
US-20250025494-A1 COMPOSITIONS FOR AND METHOD OF TREATING ACID-BASE DISORDERS SLC10A2, SLC10A1, GLS CASP2 2885/4885TSHR 3346/4885TDP1 1606/4885
US-20190209607-A1 COMPOSITIONS FOR TREATING ACID-BASE DISORDERS SLC10A2, SLC10A1, SLC26A3 CASP2 4421/4885TSHR 2261/4885TDP1 2434/4885
US-11197887-B2 Proton-binding polymers for oral administration SLC9A1, HRH2, SLC9A2 CASP2 4532/4885TSHR 1639/4885TDP1 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.