Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16539602 | 0.84 | LMNA (0.46) | WDR5KMT2ACYP2D6LMNAMAPK1 | |
| SCHEMBL2742871 | 0.77 | SOD1 (0.44) | LMNAHTT | |
| SCHEMBL16539797 | 0.77 | KDM4E (0.48) | KMT2ALMNAHTTMAOBAOC3 | |
| SCHEMBL27923626 | 0.76 | LMNA (0.40) | WDR5KMT2ACYP2D6LMNAMAPK1 | |
| SCHEMBL19962981 | 0.75 | NUDT1 (0.38) | KMT2ALMNAHTTSMN1; SMN2MAOB | |
| SCHEMBL2096242 | 0.75 | WDR5 (0.59) | WDR5KMT2ACYP2D6LMNAMAPK1 | |
| SCHEMBL4207677 | 0.73 | ALDH1A1 (0.44) | KMT2AMAPK1MEN1 | |
| SCHEMBL2970621 | 0.72 | FFAR1 (0.53) | KDM4E | |
| SCHEMBL230802 | 0.72 | TRPV4 (0.48) | — | |
| SCHEMBL2096611 | 0.72 | KMT2A (0.62) | WDR5KMT2ACYP2D6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015028960-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES AS GPR AGONISTS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2015-03-05 | — | — | WO | disclosed |