Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | CBS | P35520 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545628 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL3547165 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL10019282 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL18244613 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL3542040 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL3541625 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL102373 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL21877046 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL21876707 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 | |
| SCHEMBL31074305 | 1.00 | ALDH1A1 (0.43) | ALDH1A1BLMPMP22HSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854792-B1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2012-12-26 | — | — | EP | claimed |
| WO-2024172341-A1 | QUANTUM DOT, METHOD FOR PREPARING QUANTUM DOT, QUANTUM DOT COMPOSITION, AND ELECTRONIC DEVICE | 덕산네오룩스 주식회사 | 2024-08-22 | — | — | WO | disclosed |
| US-20240279710-A1 | FLUORESCENT PROBES | TOHOKU TECHNO ARCH CO., LTD. (JP) | 2024-08-22 | — | — | US | disclosed |
| EP-4361166-A1 | FLUORESCENT PROBES | Tohoku Techno Arch Co., Ltd. (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-117480175-A | Fluorescent probe | 东北泰克诺亚奇股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOG (CN) | 2023-05-25 | — | — | US | disclosed |
| EP-3294714-B1 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN | NEKTAR THERAPEUTICS (US) | 2023-03-15 | — | — | EP | disclosed |
| US-11111214-B2 | Kappa opioid agonists and uses thereof | NEKTAR THERAPEUTICS (US) | 2021-09-07 | — | — | US | disclosed |
| US-10766864-B2 | Morphinan derivatives for the treatment of neuropathic pain | NEKTAR THERAPEUTICS (US) | 2020-09-08 | — | — | US | disclosed |
| US-10682371-B2 | Small molecule conjugates specifically activated in tumor microenvironment for targeting and use thereof | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOGY CO. LTD. (CN) | 2020-06-16 | — | — | US | disclosed |
| US-7820693-B2 | 1-(2H)-isoquinolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20090030195-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1904462-A2 | COMPLEXES CONTAINING PERFLUOROALKYL, METHOD FOR THE PRODUCTION AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-1854792-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-11-14 | — | — | EP | disclosed |
| WO-2007009637-A2 | COMPLEXES CONTAINING PERFLUOROALKYL, THEIR USE AS CONTRAST MEDIA FOR NMR, X-RAY AND RADIO DIAGNOSIS AND RADIOTHERAPY | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-25 | — | — | WO | disclosed |
| US-20070020183-A1 | Perfluoroalkyl-containing complexes, process for their production as well as their use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-25 | — | — | US | disclosed |
| US-6080771-A | LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| US-5981558-A | ANTIMICROBIAL ACTIVITY AND ANTITUMOR ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0918058-A1 | DC 107 DERIVATIVES (1) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0887351-A1 | DC 107 DERIVATIVES (2) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020183-A1 | Perfluoroalkyl-containing complexes, process for their production as well as their use | AFF1, FRG1, AFF2 | ALDH1A1 2789/4885BLM 2263/4885PMP22 218/4885 |
| US-20240279710-A1 | FLUORESCENT PROBES | CAPN1, CAPN2, CAPNS1 | ALDH1A1 2622/4885BLM 4881/4885PMP22 3228/4885 |
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | CD47, FCGR2A, CD40 | ALDH1A1 2422/4885BLM 1823/4885PMP22 1594/4885 |
| US-10682371-B2 | Small molecule conjugates specifically activated in tumor microenvironment for targeting and use thereof | MET, ARG1, CD4 | ALDH1A1 3371/4885BLM 3197/4885PMP22 4877/4885 |
| US-10766864-B2 | Morphinan derivatives for the treatment of neuropathic pain | OPRM1, OPRL1, OPRK1 | ALDH1A1 898/4885BLM 4232/4885PMP22 393/4885 |
| US-20090030195-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | NQO1, NR5A1, SRD5A1 | ALDH1A1 371/4885BLM 924/4885PMP22 4743/4885 |
| US-11111214-B2 | Kappa opioid agonists and uses thereof | OPRK1, OPRD1, OPRM1 | ALDH1A1 782/4885BLM 4855/4885PMP22 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.