SCHEMBL16556670

SCHEMBL16556670

CCCCC1(CCCC)c2cc(/C(C)=N/OC(=O)c3ccccc3)ccc2-c2ccc([N+](=O)[O-])cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ XDH P47989 1/20 0.43
▸ MAPT P10636 12/20 0.42
▸ NPC1 O15118 5/20 0.42
▸ HTT P42858 4/20 0.42
▸ RAB9A P51151 3/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ PKM P14618 2/20 0.41
▸ CDK5 Q00535 1/20 0.41
▸ CDK5R1 Q15078 1/20 0.41
▸ MEN1 O00255 8/20 0.40
▸ KMT2A Q03164 8/20 0.40
▸ POLB P06746 4/20 0.40
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ LMNA P02545 2/20 0.40
▸ CNR1 P21554 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ GPR55 Q9Y2T6 1/20 0.40
▸ CTDSP1 Q9GZU7 1/20 0.40
▸ AHR P35869 1/20 0.39
▸ GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16550621 1.00 XDH (0.43) XDHMAPTNPC1HTTRAB9A
SCHEMBL18012804 0.90 MAPT (0.41) XDHMAPTNPC1HTTRAB9A
SCHEMBL29365660 0.89 ESPL1 (0.38) XDHMAPTHTTALDH1A1PKM
SCHEMBL16556665 0.89 ESPL1 (0.38) XDHMAPTHTTALDH1A1PKM
SCHEMBL16556668 0.87 MAPT (0.40) MAPTHTTALDH1A1MEN1KMT2A
SCHEMBL18012726 0.85 MAPT (0.44) XDHMAPTNPC1RAB9APKM
SCHEMBL18012755 0.84 KMT2A (0.39) MAPTNPC1HTTRAB9AALDH1A1
SCHEMBL17084321 0.83 MAPT (0.36) XDHMAPTNPC1HTTRAB9A
SCHEMBL18122989 0.83 MAPT (0.36) XDHMAPTNPC1HTTRAB9A
SCHEMBL18012728 0.82 MAPT (0.42) MAPTRAB9APKMCDK5CDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9316906-B2 Fluorene oxime ester compound, photopolymerization initiator and photoresist composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-04-19 — — US disclosed
US-9316906-B2 Fluorene oxime ester compound, photopolymerization initiator and photoresist composition containing the same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2016-04-19 — — US disclosed
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-04-23 — — US disclosed
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-04-23 — — US disclosed
EP-2845845-A1 NOVEL OXIMESTER FLUORINE COMPOUND, AND PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION COMPRISING SAME Korea Research Institute of Chemical Technology (KR) 2015-03-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111152-A1 NOVEL FLUORENE OXIME ESTER COMPOUND, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME PPOX, FTO, PAM XDH 2195/4885MAPT 585/4885NPC1 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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