Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16563900 | 0.85 | MAPT (0.50) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL16563778 | 0.84 | KMT2A (0.43) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16563947 | 0.82 | HDAC8 (0.47) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16563915 | 0.82 | CYP1A2 (0.54) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16563581 | 0.78 | POLB (0.52) | POLBMAPTLMNAATM | |
| SCHEMBL16563623 | 0.75 | ALOX15 (0.42) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16564040 | 0.74 | ORAI1 (0.52) | POLBMEN1KMT2ALMNAATM | |
| SCHEMBL16563605 | 0.72 | MEN1 (0.45) | ALDH1A1MEN1KMT2ALMNACYP2C9 | |
| SCHEMBL16563767 | 0.72 | ALOX15 (0.44) | — | |
| SCHEMBL16564046 | 0.70 | P2RX7 (0.47) | POLBALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848615-A1 | New pyrazole derivatives as CRAC channel modulators | Almirall, S.A. (ES) | 2015-03-18 | — | — | EP | claimed |
| EP-2848615-A1 | New pyrazole derivatives as CRAC channel modulators | Almirall, S.A. (ES) | 2015-03-18 | — | — | EP | disclosed |