SCHEMBL16611615

SCHEMBL16611615

CC(C)(C)OC(=O)N1CCN(CCON)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CHRM2 P08172 1/20 0.45
CHRM4 P08173 1/20 0.45
CHRM1 P11229 1/20 0.45
CHRM3 P20309 1/20 0.45
TLR8 Q9NR97 1/20 0.43
ACKR3 P25106 1/20 0.42
EPHX2 P34913 6/20 0.41
DDB1 Q16531 1/20 0.41
CRBN Q96SW2 1/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12605264 0.91 USP2 (0.43) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL8242595 0.86 USP2 (0.61) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL2225547 0.85 HSD11B1 (0.49) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL11344621 0.84 USP2 (0.45) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL12644325 0.83 USP2 (0.50) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL46682 0.83 USP2 (0.50) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL7605519 0.83 TLR8 (0.46) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL22123127 0.83 USP2 (0.44) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL20873847 0.83 USP2 (0.53) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL23251655 0.83 USP2 (0.46) USP2SMN1; SMN2CHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4694874-A2 GPX4 INHIBITORS AND SENOLYTIC COMPOUNDS AND USES THEREOF Rubedo Life Sciences, Inc. (US) 2026-02-18 EP disclosed
US-20260007689-A1 GPX4 Inhibitors and Senolytic Compounds and Uses Thereof RUBEDO LIFE SCIENCES INC (US) 2026-01-08 US disclosed
US-12485132-B2 GPX4 inhibitors and senolytic compounds and uses thereof Rubedo Life Sciences, Inc. (US) 2025-12-02 US disclosed
US-20250319109-A1 GPX4 Inhibitors and Senolytic Compounds and Uses Thereof RUBEDO LIFE SCIENCES INC (US) 2025-10-16 US disclosed
US-20240408124-A1 GPX4 Inhibitors and Senolytic Compounds and Uses Thereof Rubedo Life Sciences, Inc. 2024-12-12 US disclosed
WO-2024249613-A2 GPX4 INHIBITORS AND SENOLYTIC COMPOUNDS AND USES THEREOF Rubedo Life Sciences, Inc. (US) 2024-12-05 WO disclosed
US-12103928-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2024-10-01 US disclosed
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-10-19 US disclosed
US-11731971-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-08-22 US disclosed
US-20210371419-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2021-12-02 US disclosed
US-10556905-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2020-02-11 US disclosed
EP-2857401-B1 NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME MEIJI SEIKA PHARMA CO LTD (JP) 2019-09-18 EP disclosed
US-20180258089-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-09-13 US disclosed
US-10023573-B2 Beta-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-07-17 US disclosed
US-20170233393-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2017-08-17 US disclosed
US-9708320-B2 β-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2017-07-18 US disclosed
US-20160024090-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2016-01-28 US disclosed
US-9181250-B2 Beta-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-11-10 US disclosed
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-05-21 US disclosed
EP-2857401-A1 NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME Meiji Seika Pharma Co., Ltd. (JP) 2015-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731971-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 USP2 1652/4885SMN1; SMN2 702/4885CHRM2 634/4885
US-20260007689-A1 GPX4 Inhibitors and Senolytic Compounds and Uses Thereof GPX4, GPX1, PRDX4 USP2 505/4885SMN1; SMN2 1652/4885CHRM2 4143/4885
US-20160024090-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME ME1, MRPL21, FNTB USP2 2510/4885SMN1; SMN2 2245/4885CHRM2 1617/4885
US-20250319109-A1 GPX4 Inhibitors and Senolytic Compounds and Uses Thereof GPX4, GPX1, PRDX3 USP2 518/4885SMN1; SMN2 2968/4885CHRM2 4761/4885
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME ME1, FN1, FNTB USP2 2674/4885SMN1; SMN2 2493/4885CHRM2 1277/4885
US-20210371419-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 USP2 1652/4885SMN1; SMN2 702/4885CHRM2 634/4885
US-20180258089-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 USP2 1652/4885SMN1; SMN2 702/4885CHRM2 634/4885
US-10023573-B2 Beta-lactamase inhibitor and process for preparing the same FN1, FNTB, CPN1 USP2 669/4885SMN1; SMN2 1523/4885CHRM2 1270/4885
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 USP2 1652/4885SMN1; SMN2 702/4885CHRM2 634/4885
US-12103928-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 USP2 1652/4885SMN1; SMN2 702/4885CHRM2 634/4885
US-20240408124-A1 GPX4 Inhibitors and Senolytic Compounds and Uses Thereof GPX4, GPX1, PRDX3 USP2 518/4885SMN1; SMN2 2968/4885CHRM2 4761/4885
US-12485132-B2 GPX4 inhibitors and senolytic compounds and uses thereof GPX4, GPX1, PRDX3 USP2 518/4885SMN1; SMN2 2968/4885CHRM2 4761/4885
US-10556905-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 USP2 1652/4885SMN1; SMN2 702/4885CHRM2 634/4885
US-20170233393-A1 BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME FN1, FNTB, CPN1 USP2 669/4885SMN1; SMN2 1523/4885CHRM2 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.