Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244957 | 0.86 | MAPK1 (0.64) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL1208061 | 0.82 | MAPK1 (0.67) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29557693 | 0.82 | MAPK1 (0.67) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL24860289 | 0.78 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL22778911 | 0.78 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29378413 | 0.78 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL241700 | 0.76 | KMT2A (0.53) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29387322 | 0.76 | KMT2A (0.53) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15007308 | 0.76 | MAPK1 (0.53) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29387164 | 0.76 | KMT2A (0.53) | MAPK1MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857503-B1 | METHOD FOR STABILIZING ASCORBIC ACID OXIDASE | KYOWA MEDEX CO LTD (JP) | 2018-01-10 | — | — | EP | disclosed |
| US-9546363-B2 | Method for stabilizing ascorbic acid oxidase | KYOWA MEDEX CO., LTD. (JP) | 2017-01-17 | — | — | US | disclosed |
| US-20150147798-A1 | METHOD FOR STABILIZING ASCORBIC ACID OXIDASE | CANON MEDICAL DIAGNOSTICS CORPORATION (JP) | 2015-05-28 | — | — | US | disclosed |
| EP-2857503-A1 | METHOD FOR STABILIZING ASCORBIC ACID OXIDASE | Kyowa Medex Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |