Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | FOS | P01100 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22616307 | 0.97 | PTPN1 (0.57) | PTPN1TAAR1TSHRMAPK1FOS | |
| SCHEMBL119627 | 0.92 | CYP1A2 (0.56) | PTPN1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28304313 | 0.92 | PTPN1 (0.53) | PTPN1TAAR1TSHRMAPK1FOS | |
| SCHEMBL29873001 | 0.92 | CYP1A2 (0.56) | PTPN1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29873336 | 0.91 | CYP1A2 (0.58) | ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL117978 | 0.91 | CYP1A2 (0.58) | ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL14763888 | 0.90 | PTPN1 (0.54) | PTPN1TAAR1TSHRMAPK1FOS | |
| SCHEMBL29602123 | 0.90 | PTPN1 (0.54) | PTPN1TAAR1TSHRMAPK1FOS | |
| SCHEMBL117401 | 0.90 | PTPN1 (0.54) | PTPN1TAAR1TSHRMAPK1FOS | |
| SCHEMBL27976302 | 0.90 | ALDH1A1 (0.54) | PTPN1TAAR1TSHRMAPK1FOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306429-B1 | THROAT DROPS SUITABLE FOR RELIEF OF COUGH AND COLD SYMPTOMS | THE PROCTER & GAMBLE COMPANY | 2001-10-23 | — | — | US | claimed |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | SYMRISE AG (DE) | 2024-01-04 | — | — | US | disclosed |
| US-9446267-B2 | Products comprising a flavoring agent composition | SYMRISE AG (DE) | 2016-09-20 | — | — | US | disclosed |
| US-8496950-B2 | Mixture containing menthol | SYMRISE AG (DE) | 2013-07-30 | — | — | US | disclosed |
| US-8242289-B2 | Alkyl-substituted tetrahydropyrans as flavoring substances | SYMRISE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20120128744-A1 | MIXTURE CONTAINING MENTHOL | SYMRISE AG (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20110081303-A1 | TEETH CLEANING COMPOUND CONTAINING MENTHOL WITH REDUCED BITTER SENSATION | SYMRISE AG (DE) | 2011-04-07 | — | — | US | disclosed |
| US-20100226864-A1 | ALKYL-SUBSTITUTED TETRAHYDROPYRANS AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226864-A1 | ALKYL-SUBSTITUTED TETRAHYDROPYRANS AS FLAVORING SUBSTANCES | TAS1R3, TAS2R10, TAS2R50 | PTPN1 2991/4885TAAR1 42/4885TSHR 2939/4885 |
| US-20240000746-A1 | New Cooling Agents and Preparations Containing Them | TTPA, TREH, TAS2R45 | PTPN1 3398/4885TAAR1 2536/4885TSHR 1885/4885 |
| US-20110081303-A1 | TEETH CLEANING COMPOUND CONTAINING MENTHOL WITH REDUCED BITTER SENSATION | TAS2R10, TAS2R30, TAS2R14 | PTPN1 4618/4885TAAR1 152/4885TSHR 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.