Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566515 | 1.00 | TAAR1 (0.46) | TAAR1IDO1TSHRGPR52CYP1A2 | |
| SCHEMBL2478901 | 0.84 | ALDH1A1 (0.40) | TAAR1IDO1TSHRCYP1A2CYP2D6 | |
| SCHEMBL28879956 | 0.82 | GABRA1 (0.43) | TAAR1IDO1TSHRGPR52CYP1A2 | |
| SCHEMBL7461135 | 0.82 | TDP1 (0.38) | TSHRCYP2D6ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7654186 | 0.81 | TSHR (0.38) | TAAR1IDO1TSHRCYP1A2CYP2D6 | |
| SCHEMBL430886 | 0.79 | CA2 (0.43) | ALDH1A1MAPTHTTLMNAKMT2A | |
| SCHEMBL1759301 | 0.79 | PARP1 (0.40) | TAAR1IDO1TSHRALDH1A1MAPT | |
| SCHEMBL1849111 | 0.79 | GABRA1 (0.35) | TAAR1IDO1TSHRGABRA1GABRB2 | |
| SCHEMBL3408932 | 0.79 | GABRA1 (0.35) | TAAR1IDO1TSHRCYP1A2CYP2D6 | |
| SCHEMBL1701340 | 0.79 | GABRA1 (0.40) | TAAR1IDO1TSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808100-A | Indole alkaloid compound and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2020-10-23 | — | — | CN | claimed |
| CN-111233908-A | Benzoxaborol-1-ol compound and preparation method and application thereof | 南京农业大学 | 2020-06-05 | — | — | CN | claimed |
| WO-2012164572-A1 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-12-06 | — | — | WO | claimed |
| EP-1868604-A2 | REGULATION OF PROTEIN SYNTHESIS BY INHIBITION OF EIF4E-EIF4G INTERACTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-12-26 | — | — | EP | claimed |
| WO-2006078942-A2 | REGULATION OF PROTEIN SYNTHESIS BY INHIBITION OF EIF4E-EIF4G INTERACTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-07-27 | — | — | WO | claimed |
| US-20030050330-A1 | 4,5-subtstituted imdazolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. | 2003-03-13 | — | — | US | claimed |
| US-6426360-B1 | ANTIARTHRITIC AGENTS | G D SEARLE & CO. | 2002-07-30 | — | — | US | claimed |
| EP-1211244-A2 | 4,5-substitued imidazolyl compounds for the treatment of inflammation | G.D. Searle & Co. (US) | 2002-06-05 | — | — | EP | claimed |
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | claimed |
| WO-1996003387-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | claimed |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| EP-3843728-B1 | INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN | MORPHIC THERAPEUTIC INC (US) | 2025-04-30 | — | — | EP | disclosed |
| US-20250090440-A1 | NOVEL CYCLIC ACETAL COMPOUNDS WITH ALDEHYDE OR KETONE FUNCTIONALITIES AND USES THEREOF | Structure Holdings, LLC (US) | 2025-03-20 | — | — | US | disclosed |
| US-20250032462-A1 | BAX ACTIVATORS AND USES THEREOF IN CANCER THERAPY | ALBERT EINSTEIN COLLEGE MEDICINE (US) | 2025-01-30 | — | — | US | disclosed |
| EP-4422619-A1 | INHIBITORS OF VIRAL HELICASES BINDING TO A NOVEL ALLOSTERIC BINDING SITE | Eisbach Bio GmbH (DE) | 2024-09-04 | — | — | EP | disclosed |
| US-4670443-A | Benzo(f)isoquinoline compounds useful as calcium entry blockers | MERCK & CO., INC. (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0151826-A1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-08-21 | — | — | EP | disclosed |
| US-4532237-A | Treating cardiovascular disorders | MERCK & CO., INC. (US) | 1985-07-30 | — | — | US | disclosed |
| EP-0145037-A2 | N-(bicyclic heterocyclyl)-4-piperidinamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-06-19 | — | — | EP | disclosed |
| US-3951662-A | Method of antistatic treatment for silver halide photosensitive materials | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050330-A1 | 4,5-subtstituted imdazolyl compounds for the treatment of inflammation | AHR, HACL2, IRAK2 | TAAR1 585/4885IDO1 57/4885TSHR 2435/4885 |
| US-20250032462-A1 | BAX ACTIVATORS AND USES THEREOF IN CANCER THERAPY | BAX, BAD, BID | TAAR1 4863/4885IDO1 4797/4885TSHR 4621/4885 |
| US-20250090440-A1 | NOVEL CYCLIC ACETAL COMPOUNDS WITH ALDEHYDE OR KETONE FUNCTIONALITIES AND USES THEREOF | OR51E2, TAS2R5, TRPA1 | TAAR1 79/4885IDO1 2054/4885TSHR 2960/4885 |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | TAAR1 2444/4885IDO1 1848/4885TSHR 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.