SCHEMBL166191

SCHEMBL166191

O=C(O)c1ccccc1C1C2CC3CC(C2)CC1(c1ccccc1C(=O)O)C3

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
P2RX7 Q99572 2/20 0.37
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HSD11B1 P28845 2/20 0.35
FAAH O00519 2/20 0.35
EPHX2 P34913 3/20 0.35
EPHX1 P07099 1/20 0.35
HIF1A Q16665 1/20 0.34
EPAS1 Q99814 1/20 0.34
HSD11B2 P80365 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1269355 0.76 MAPT (0.37) KDM4EP2RX7ALDH1A1MAPTHPGD
SCHEMBL30978073 0.76 MAPT (0.37) KDM4EP2RX7ALDH1A1MAPTHPGD
SCHEMBL5475249 0.75 KDM4E (0.53) KDM4EP2RX7ALDH1A1MAPTHPGD
Acrylic Acid SCHEMBL11105271 0.74 ALDH1A1 (0.36) KDM4EP2RX7ALDH1A1MAPTHPGD
SCHEMBL28223258 0.71 ALDH1A1 (0.45) KDM4ECYP2C9ALDH1A1MAPTHPGD
SCHEMBL3103198 0.70 KDM4E (0.43) KDM4EP2RX7ALDH1A1MAPTHPGD
Hydrochloric Acid SCHEMBL2710119 0.70 CYP2C9 (0.44) KDM4ECYP2C9ALDH1A1MAPTHPGD
SCHEMBL6853710 0.69 KDM4E (0.42) KDM4EP2RX7ALDH1A1MAPTHPGD
SCHEMBL30855591 0.69
SCHEMBL2747082 0.69 KDM4E (0.47) KDM4EP2RX7ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 EP claimed
US-20140311507-A1 Porous Catalytic Matrices for Elimination of Toxicants Found in Tobacco Combustion Products MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 US claimed
EP-2739169-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS Massachusetts Institute Of Technology (US) 2014-06-11 EP claimed
WO-2013019865-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
US-12630567-B2 High yield synthesis of metal-organic frameworks ExxonMobil Technology and Engineering Company (US) 2026-05-19 US disclosed
US-20250276300-A1 REDUCTION OF MONOMERIC ISOCYANATES BY POROUS MATERIAL BASF SE (DE) 2025-09-04 US disclosed
EP-4291588-B1 REDUCTION OF MONOMERIC ISOCYANATES BY POROUS MATERIAL BASF SE (DE) 2025-08-20 EP disclosed
CN-112352334-B Cathode for lithium-sulfur battery and cathode for sodium-sulfur battery 约翰霍普金斯大学 2025-03-25 CN disclosed
US-12227526-B2 Metal-organic framework materials comprising a diimine scaffold and methods for production thereof ExxonMobil Technology and Engineering Company (US) 2025-02-18 US disclosed
EP-3947396-B1 METAL-ORGANIC FRAMEWORK MATERIALS COMPRISING A DIIMINE SCAFFOLD AND METHODS FOR PRODUCTION THEREOF EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2024-12-11 EP disclosed
US-20240336636-A1 METAL-ORGANIC FRAMEWORK THE UNIVERSITY OF LIVERPOOL (GB) 2024-10-10 US disclosed
US-12107210-B2 Lithium-sulfur and sodium-sulfur battery cathodes THE JOHNS HOPKINS UNIVERSITY (US) 2024-10-01 US disclosed
EP-1689670-A1 METHOD FOR THE CONTROLLED STORAGE AND RELEASE OF GASES USING AN ELECTROCHEMICALLY PRODUCED CRYSTALLINE, POROUS, ORGANOMETALLIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-08-16 EP disclosed
EP-1687462-A1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-08-09 EP disclosed
WO-2006072573-A2 ADSORPTIVE PRODUCTION OF XENON FROM KRYPTON/XENON GAS MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 WO disclosed
EP-1674555-A1 Concentration of methane in methane containing gas mixtures by adsorption BASF AKTIENGESELLSCHAFT (DE) 2006-06-28 EP disclosed
WO-2005049484-A1 METHOD FOR THE CONTROLLED STORAGE AND RELEASE OF GASES USING AN ELECTROCHEMICALLY PRODUCED CRYSTALLINE, POROUS, ORGANOMETALLIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 WO disclosed
WO-2005049892-A1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 WO disclosed
EP-1471997-A1 METHOD FOR STORING, ABSORBING AND EMITTING GASES USING NOVEL FRAMEWORK MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2004-11-03 EP disclosed
WO-2003064030-A1 METHOD FOR STORING, ABSORBING AND EMITTING GASES USING NOVEL FRAMEWORK MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12227526-B2 Metal-organic framework materials comprising a diimine scaffold and methods for production thereof PICALM, ILK, CAD KDM4E 3487/4885P2RX7 3130/4885CYP2C9 2777/4885
US-12630567-B2 High yield synthesis of metal-organic frameworks ODC1, POF1B, DDC KDM4E 1783/4885P2RX7 3609/4885CYP2C9 2941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.