Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624686 | 0.93 | NPC1 (0.44) | MEN1KMT2ANLRP3NPC1RAB9A | |
| SCHEMBL16627140 | 0.89 | KIF11 (0.41) | MEN1KMT2ANLRP3NPC1RAB9A | |
| SCHEMBL19020519 | 0.86 | TDP1 (0.46) | MEN1KMT2AABCG2ABCB1TAAR1 | |
| SCHEMBL16627145 | 0.80 | LTA4H (0.41) | KMT2ANPC1RAB9ALMNAHTT | |
| SCHEMBL16624847 | 0.76 | CASP3 (0.50) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL19020517 | 0.76 | KIF11 (0.43) | BCHE | |
| SCHEMBL20101406 | 0.76 | FFAR1 (0.41) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL19021001 | 0.75 | LTA4H (0.46) | KMT2ANPC1RAB9ALMNAHTT | |
| SCHEMBL28241152 | 0.75 | LTA4H (0.52) | NPC1RAB9AABCB1TDP1L3MBTL1 | |
| SCHEMBL16627149 | 0.73 | GAA (0.48) | MEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051366-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |