Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624686 | 0.95 | NPC1 (0.44) | KIF11NPC1RAB9AALDH1A1TERT | |
| SCHEMBL16624800 | 0.89 | MEN1 (0.42) | NPC1RAB9AALDH1A1TERTLMNA | |
| SCHEMBL19020521 | 0.85 | KIF11 (0.50) | KIF11LMNAHTTSMN1; SMN2MAOB | |
| SCHEMBL16627145 | 0.84 | LTA4H (0.41) | KIF11NPC1RAB9ALMNAHTT | |
| SCHEMBL16628094 | 0.78 | CYP11B1 (0.45) | NPC1RAB9AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28241152 | 0.77 | LTA4H (0.52) | KIF11NPC1RAB9AMAOBLTA4H | |
| SCHEMBL16624847 | 0.76 | CASP3 (0.50) | KIF11NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL16627149 | 0.75 | GAA (0.48) | HTTSMN1; SMN2MEN1KMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL30186367 | 0.75 | LTA4H (0.50) | KIF11NPC1RAB9AMAOBLTA4H | |
| SCHEMBL17954315 | 0.75 | CASP3 (0.46) | NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |