Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627880 | 0.86 | HDAC1 (0.47) | MEN1KMT2AMAPTTP53P2RX7 | |
| SCHEMBL16627803 | 0.82 | F10 (0.47) | MEN1KMT2AMAPTTP53P2RX7 | |
| SCHEMBL16627877 | 0.76 | MAPT (0.47) | MEN1KMT2AMAPTTP53P2RX7 | |
| SCHEMBL16627754 | 0.75 | RAB9A (0.49) | MEN1KMT2AMAPTLMNAP2RX7 | |
| SCHEMBL16627749 | 0.73 | MEN1 (0.58) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL16627806 | 0.73 | NHERF1 (0.49) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL16627814 | 0.71 | F10 (0.48) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL16627656 | 0.70 | F10 (0.47) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL16627823 | 0.70 | NPY5R (0.47) | MEN1KMT2AMAPTTP53P2RX7 | |
| SCHEMBL16627753 | 0.69 | ABCG2 (0.51) | MEN1KMT2AMAPTPOLBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |