Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 3/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15231711 | 0.87 | HTR2A (0.48) | HTR2AHTR2CKCNH2PRKAA2KDM1A | |
| SCHEMBL4771117 | 0.82 | SPR (0.48) | HTR2AHTR2CKCNH2EPHX2SPR | |
| SCHEMBL27917812 | 0.82 | HTR2A (0.58) | HTR2AHTR2CKCNH2SPRCTSS | |
| SCHEMBL15232168 | 0.81 | GPR119 (0.59) | — | |
| SCHEMBL2928335 | 0.81 | ELOVL6 (0.45) | HTR2AHTR2CKCNH2SPR | |
| SCHEMBL4106774 | 0.81 | HTR2A (0.56) | HTR2AHTR2CKCNH2EPHX2SPR | |
| SCHEMBL5428002 | 0.81 | CA12 (0.44) | HTR2AHTR2CKCNH2EPHX2SPR | |
| SCHEMBL2931624 | 0.81 | SPR (0.53) | HTR2AHTR2CKCNH2EPHX2SPR | |
| SCHEMBL2634144 | 0.81 | SPR (0.44) | HTR2AHTR2CKCNH2EPHX2SPR | |
| SCHEMBL16820354 | 0.80 | CTSS (0.44) | HTR2AHTR2CKCNH2CCR6PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | Valo Health, LLC | 2020-06-30 | — | — | US | disclosed |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | VALO HEALTH, INC. | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | STS, SQOR, SULT1E1 | HTR2A 2215/4885HTR2C 1288/4885KCNH2 2669/4885 |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | STS, SULT1E1, CBS | HTR2A 2425/4885HTR2C 1519/4885KCNH2 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.