Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661047 | 0.86 | GRIN2D (0.35) | PTGS2GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL29852250 | 0.83 | PTGS2 (0.40) | PTGS2PTGS1POLBCYP3A4HPGD | |
| SCHEMBL1291782 | 0.83 | PTGS2 (0.40) | PTGS2PTGS1POLBCYP3A4HPGD | |
| SCHEMBL1292040 | 0.81 | ALDH1A1 (0.46) | PTGS2POLBHPGD | |
| SCHEMBL1292044 | 0.75 | PTGS2 (0.38) | PTGS2POLBCYP3A4HPGD | |
| SCHEMBL1292020 | 0.75 | CYP3A4 (0.47) | PTGS2PTGS1POLBCYP3A4HPGD | |
| SCHEMBL1292011 | 0.72 | MCHR1 (0.36) | POLBCYP3A4 | |
| SCHEMBL1663351 | 0.72 | ALDH1A1 (0.41) | PTGS2PTGS1HPGD | |
| SCHEMBL19005894 | 0.70 | PTGS2 (0.35) | PTGS2PTGS1POLBCYP3A4 | |
| SCHEMBL1291722 | 0.70 | PTGS2 (0.35) | PTGS2PTGS1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624811-B1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH & CIE (CH) | 2017-06-21 | — | — | EP | disclosed |
| EP-2624811-B1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH & CIE (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| WO-2012045646-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | TRPA1, BBOX1, PAOX | PTGS2 771/4885GRIN2D 1555/4885GRIN2A 3105/4885 |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | BBOX1, CBR3, CBR1 | PTGS2 914/4885GRIN2D 2092/4885GRIN2A 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.