Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 6/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634734 | 0.74 | DAO (0.50) | DAOFEN1 | |
| SCHEMBL16634793 | 0.70 | DAO (0.43) | DAOFEN1HSP90AA1 | |
| SCHEMBL10222518 | 0.67 | ALB (0.55) | NOTUM | |
| SCHEMBL16634615 | 0.65 | RORC (0.46) | DAOHSP90AA1 | |
| SCHEMBL13954881 | 0.63 | DAO (0.64) | DAOFEN1 | |
| SCHEMBL13015570 | 0.63 | DAO (0.46) | DAODHODH | |
| SCHEMBL16634634 | 0.62 | KEAP1 (0.46) | — | |
| SCHEMBL161622 | 0.62 | ALOX15 (0.53) | NOTUM | |
| SCHEMBL4942021 | 0.62 | CYP1A2 (0.50) | NOTUM | |
| SCHEMBL30615321 | 0.60 | DAO (0.48) | DAOFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |