Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 4/20 | 0.44 |
| ▸ | GABRD | O14764 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.44 |
| ▸ | GABRE | P78334 | 4/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634676 | 0.84 | TP53 (0.53) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL16634744 | 0.77 | L3MBTL1 (0.55) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL8156714 | 0.75 | GABRP (0.52) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL29367625 | 0.75 | LMNA (0.65) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL699273 | 0.75 | LMNA (0.65) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL30615654 | 0.75 | GABRP (0.52) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL14199033 | 0.74 | GABRP (0.51) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL21463893 | 0.74 | PGR (0.49) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL21463914 | 0.74 | ALDH1A1 (0.49) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL30615608 | 0.74 | ALDH1A1 (0.49) | HSP90AA1MEN1LMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |