Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16308645 | 1.00 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL145547 | 1.00 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL11784673 | 1.00 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL9816852 | 0.97 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL3856010 | 0.97 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL29369084 | 0.97 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL4132279 | 0.97 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL10993478 | 0.97 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL3855244 | 0.97 | DGKA (0.59) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL9248327 | 0.96 | MGLL (0.62) | DGKAMGLLCNR2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10231985-B2 | Compounds and compositions comprising such compounds for the prevention or treatment of dyslipidaemias | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-03-19 | — | — | US | claimed |
| EP-3065733-B1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NAT RECH SCIENT (FR) | 2018-05-30 | — | — | EP | claimed |
| EP-3065732-B1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NAT RECH SCIENT (FR) | 2018-04-11 | — | — | EP | claimed |
| US-20160287542-A1 | COMPOUNDS, COMPOSITIONS AND CORRESPONDING USES FOR PREVENTING AND/OR TREATING OF DYSLIPIDEMIA | UNIVERSITE DE POITIERS (FR) | 2016-10-06 | — | — | US | claimed |
| EP-3065732-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-09-14 | — | — | EP | claimed |
| EP-3065733-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | Centre National De La Recherche Scientifique (FR) | 2016-09-14 | — | — | EP | claimed |
| US-20160256429-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-09-08 | — | — | US | claimed |
| WO-2015052237-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-04-16 | — | — | WO | claimed |
| WO-2015052433-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-04-16 | — | — | WO | claimed |
| US-10231985-B2 | Compounds and compositions comprising such compounds for the prevention or treatment of dyslipidaemias | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-03-19 | — | — | US | disclosed |
| US-10156566-B2 | Detoxification of microbial virulence factors in oral cavity | THE PROCTER & GAMBLE COMPANY (US) | 2018-12-18 | — | — | US | disclosed |
| EP-3065733-B1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NAT RECH SCIENT (FR) | 2018-05-30 | — | — | EP | disclosed |
| EP-3065732-B1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NAT RECH SCIENT (FR) | 2018-04-11 | — | — | EP | disclosed |
| US-9821000-B2 | Compounds, compositions and corresponding uses for preventing and/or treating of dyslipidemia | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2017-11-21 | — | — | US | disclosed |
| EP-3065732-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-09-14 | — | — | EP | disclosed |
| EP-3065733-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | Centre National De La Recherche Scientifique (FR) | 2016-09-14 | — | — | EP | disclosed |
| US-20160256429-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-09-08 | — | — | US | disclosed |
| CN-105754696-A | Anti-rust lubricating grease for pump thread hole | 安徽埃斯克制泵有限公司 | 2016-07-13 | — | — | CN | disclosed |
| WO-2015052237-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052433-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287542-A1 | COMPOUNDS, COMPOSITIONS AND CORRESPONDING USES FOR PREVENTING AND/OR TREATING OF DYSLIPIDEMIA | LIPC, CPT1A, LIPA | DGKA 1043/4885PRKCE 1347/4885PRKCQ 1822/4885 |
| US-20160256429-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | LIPC, FABP4, PNLIP | DGKA 195/4885PRKCE 641/4885PRKCQ 770/4885 |
| US-10156566-B2 | Detoxification of microbial virulence factors in oral cavity | GSTM2, GSTA2, GSTA1 | DGKA 2169/4885PRKCE 4078/4885PRKCQ 3681/4885 |
| US-10231985-B2 | Compounds and compositions comprising such compounds for the prevention or treatment of dyslipidaemias | LIPC, FABP4, PNLIP | DGKA 195/4885PRKCE 641/4885PRKCQ 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.