Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 2/20 | 0.33 |
| ▸ | PPM1B | O75688 | 2/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.33 |
| ▸ | PPP5C | P53041 | 2/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601537 | 0.71 | TP53 (0.48) | TP53LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL21987140 | 0.71 | TP53 (0.48) | TP53LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3818615 | 0.70 | CRBN (0.30) | — | |
| SCHEMBL12911264 | 0.67 | SLC6A3 (0.31) | SLC6A3 | |
| SCHEMBL561422 | 0.67 | TSHR (0.32) | TSHR | |
| SCHEMBL304318 | 0.67 | CEL (0.33) | TSHRPTPN1KMT2A | |
| SCHEMBL10759055 | 0.67 | TSHR (0.32) | TSHR | |
| SCHEMBL346876 | 0.67 | TSHR (0.32) | TSHR | |
| SCHEMBL6520826 | 0.65 | ALOX15 (0.32) | TDP1TSHR | |
| SCHEMBL2647824 | 0.65 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307476-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-04-13 | — | — | EP | claimed |
| WO-2009152068-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2009-12-17 | — | — | WO | claimed |
| US-20090312470-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2009-12-17 | — | — | US | claimed |
| WO-2011071674-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-06-16 | — | — | WO | disclosed |
| EP-2307476-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20100113664-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2009152068-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |
| US-20090312470-A1 | Asymmetric Cyclic Diester Compounds | FERRO CORPORATION (US) | 2009-12-17 | — | — | US | disclosed |
| US-20080306230-A1 | Composition and Associated Method | GENERAL ELECTRIC COMPANY (US) | 2008-12-11 | — | — | US | disclosed |
| US-4132697-A | LIQUID IMPREGNANT AS A FIBER REINFORCING BINDER | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4041004-A | Polyepoxy-3,3',4,4'-benzhydrol tetracarboxylic dianhydride laminating resins | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-3996185-A | Polyepoxy resin-diaryl dianhydride laminating resins and laminates | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312470-A1 | Asymmetric Cyclic Diester Compounds | DDT, PCNA, AADAC | TP53 2535/4885LMNA 3399/4885RAB9A 4690/4885 |
| US-20080306230-A1 | Composition and Associated Method | COX6C, GRIA4, CYCS | TP53 4750/4885LMNA 3758/4885RAB9A 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.