Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122272 | 0.80 | MAOB (0.59) | CYP3A4CHRNB2CHRNA4MAOBMAPT | |
| SCHEMBL16652173 | 0.79 | ABL1 (0.44) | CYP2A6CYP3A4CHRNB2CHRNA4MAPT | |
| SCHEMBL10417191 | 0.79 | ALOX5 (0.51) | CYP2A6CYP3A4CHRNB2CHRNA4MAPT | |
| SCHEMBL20284826 | 0.78 | CHKA (0.42) | MAOBMAPTNPSR1TSHRTDP1 | |
| SCHEMBL2731119 | 0.76 | MAPT (0.73) | CHRNB2CHRNA4MAOBMAPTTDP1 | |
| SCHEMBL13260410 | 0.72 | MAOB (0.54) | MAOBMAPTNPSR1TSHRTDP1 | |
| SCHEMBL31065089 | 0.69 | MAOB (0.51) | CYP3A4CHRNB2CHRNA4MAOBMAPT | |
| SCHEMBL27681500 | 0.69 | MAPT (0.73) | CYP2A6CYP3A4MAOBMAPTTDP1 | |
| SCHEMBL31415059 | 0.68 | ADRB1 (0.44) | CYP3A4MAOBMAPTNPSR1TSHR | |
| SCHEMBL30720445 | 0.68 | CHRNB2 (0.45) | CYP2A6CYP2E1CYP3A4CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101392-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2017-04-13 | — | — | US | disclosed |
| US-9611247-B2 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20160031850-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC | 2016-02-04 | — | — | US | disclosed |
| US-9249122-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC | 2016-02-02 | — | — | US | disclosed |
| US-9199964-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150250177-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-09-10 | — | — | US | disclosed |
| US-9108946-B2 | Processes for the preparation of pesticidal compounds | DOW AGROSCIENCES LLC (US) | 2015-08-18 | — | — | US | disclosed |
| US-20150112078-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150112078-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | CYP2A6 457/4885CYP2E1 111/4885CYP3A4 98/4885 |
| US-20170101392-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | CYP2A6 457/4885CYP2E1 111/4885CYP3A4 98/4885 |
| US-20160031850-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | PPOX, PDXK, CYP4Z1 | CYP2A6 902/4885CYP2E1 12/4885CYP3A4 26/4885 |
| US-20150250177-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, ACHE, PTMS | CYP2A6 457/4885CYP2E1 111/4885CYP3A4 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.