Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654050 | 0.86 | LMNA (0.49) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL16654048 | 0.84 | LMNA (0.44) | ALDH1A1MEN1GAAKMT2ATSHR | |
| SCHEMBL16654083 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL18155097 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL16654268 | 0.67 | OPRM1 (0.48) | ALDH1A1GAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL13900631 | 0.67 | ALDH1A1 (0.52) | ALDH1A1MEN1GAAKMT2ATSHR | |
| SCHEMBL14761125 | 0.66 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNAHPGDNPSR1 | |
| SCHEMBL8888284 | 0.65 | MCL1 (0.65) | ALDH1A1GAATSHRLMNAMCL1 | |
| SCHEMBL4439807 | 0.65 | RAB9A (0.61) | ALDH1A1MEN1GAAKMT2ATSHR | |
| SCHEMBL17294652 | 0.65 | HTT (0.55) | ALDH1A1MEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160255836-A1 | N-CYCLOALKYL-N-(BIHETEROCYCLYMETHYLENE)-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-09-08 | — | — | US | claimed |
| EP-3057423-A2 | N-CYCLOALKYL-N-(BIHETEROCYCLYMETHYLENE)-(THIO)CARBOXAMIDE DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-24 | — | — | EP | claimed |
| WO-2015055706-A2 | N-CYCLOALKYL-N-(BIHETEROCYCLYMETHYLENE)-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | claimed |
| US-10076116-B2 | N-cycloalkyl-N-(biheterocyclymethylene)-(thio)carboxamide derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-18 | — | — | US | disclosed |
| US-20160255836-A1 | N-CYCLOALKYL-N-(BIHETEROCYCLYMETHYLENE)-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-09-08 | — | — | US | disclosed |
| EP-3057423-A2 | N-CYCLOALKYL-N-(BIHETEROCYCLYMETHYLENE)-(THIO)CARBOXAMIDE DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015055706-A2 | N-CYCLOALKYL-N-(BIHETEROCYCLYMETHYLENE)-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10076116-B2 | N-cycloalkyl-N-(biheterocyclymethylene)-(thio)carboxamide derivatives | CBR3, CYP51A1, NIT2 | ALDH1A1 3279/4885MEN1 3921/4885GAA 1319/4885 |
| US-20160255836-A1 | N-CYCLOALKYL-N-(BIHETEROCYCLYMETHYLENE)-(THIO)CARBOXAMIDE DERIVATIVES | CBR3, CYP51A1, NIT2 | ALDH1A1 3279/4885MEN1 3921/4885GAA 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.