Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368547 | 0.84 | L3MBTL1 (0.49) | SLC6A7L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL31589397 | 0.84 | HTR1A (0.52) | SLC6A7L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL22527481 | 0.83 | L3MBTL1 (0.57) | SLC6A7L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL6644278 | 0.80 | GPR119 (0.68) | SLC6A7GPR119 | |
| SCHEMBL5237158 | 0.80 | KMT2A (0.68) | SLC6A7MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21553750 | 0.76 | POLB (0.45) | SLC6A7L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL7090347 | 0.76 | GPR119 (0.62) | SLC6A7GPR119 | |
| SCHEMBL6644916 | 0.75 | LMNA (0.56) | SLC6A7KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL3409601 | 0.75 | PIK3CA (0.54) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL6787637 | 0.75 | HTR7 (0.54) | SLC6A7KDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057969-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT | Blueprint Medicines Corporation (US) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015057873-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT | BLUEPRINT MEDICINES CORPORATION (US) | 2015-04-23 | — | — | WO | disclosed |