Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965650 | 0.84 | KDM4E (0.64) | SLC26A4POLBGAATSHRSMN1; SMN2 | |
| SCHEMBL3976556 | 0.77 | SLC26A4 (0.69) | SLC26A4KMT2AMEN1BLMATM | |
| SCHEMBL2772042 | 0.77 | HSD11B1 (0.50) | SLC26A4KMT2AMEN1BLMATM | |
| SCHEMBL2083566 | 0.75 | ALDH1A1 (0.54) | LMNAHTTPOLBGAATSHR | |
| SCHEMBL30664708 | 0.74 | SLC26A4 (0.65) | SLC26A4KMT2AMEN1BLMATM | |
| SCHEMBL26676637 | 0.74 | SLC26A4 (0.65) | SLC26A4KMT2AMEN1BLMATM | |
| SCHEMBL26676568 | 0.74 | SLC26A4 (0.65) | SLC26A4KMT2AMEN1BLMATM | |
| SCHEMBL24470655 | 0.73 | CASP3 (0.84) | SLC26A4KMT2AMEN1BLMATM | |
| SCHEMBL29713158 | 0.73 | CASP3 (0.84) | SLC26A4KMT2AMEN1BLMATM | |
| SCHEMBL26676598 | 0.73 | LMNA (0.65) | SLC26A4KMT2AMEN1BLMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |