SCHEMBL16664371

SCHEMBL16664371

O=S(=O)(c1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1)c1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
HTR6 P50406 6/20 0.40
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
TRPV4 Q9HBA0 1/20 0.38
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
AGTR1 P30556 1/20 0.36
PTPN1 P18031 2/20 0.36
HDAC4 P56524 1/20 0.35
SRC P12931 1/20 0.35
PRKACA P17612 1/20 0.35
PRKACG P22612 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16724442 1.00 KDM4E (0.50) KDM4EATML3MBTL1CA12CA1
SCHEMBL16724444 1.00 KDM4E (0.50) KDM4EATML3MBTL1CA12CA1
SCHEMBL30785606 0.91 KDM4E (0.59) KDM4EATML3MBTL1CA12CA1
SCHEMBL12937259 0.91 KDM4E (0.59) KDM4EATML3MBTL1CA12CA1
SCHEMBL27959943 0.90 KDM4E (0.52) KDM4EATML3MBTL1CA12CA1
SCHEMBL16664362 0.90 KDM4E (0.45) KDM4EATML3MBTL1CA12CA1
SCHEMBL14649192 0.90 KDM4E (0.51) KDM4EATML3MBTL1CA12CA1
SCHEMBL17109696 0.89 KDM4E (0.46) KDM4EATML3MBTL1CA12CA1
SCHEMBL22523880 0.89 USP14 (0.42) KDM4EATML3MBTL1HTR6
SCHEMBL16664369 0.89 HSD11B1 (0.40) KDM4EATML3MBTL1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170018600-A1 ORGANIC LIGHT-EMITTING DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-19 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20150270494-A1 Terminally Activated Delayed Fluorescence Material, A Method Of Synthesizing The Same and An OLED Device Using The Same Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-09-24 US disclosed
US-20150270494-A1 Terminally Activated Delayed Fluorescence Material, A Method Of Synthesizing The Same and An OLED Device Using The Same Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-09-24 US disclosed
US-20150141642-A1 LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2015-05-21 US disclosed
US-20150141642-A1 LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2015-05-21 US disclosed
EP-2862913-A1 LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2015-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 KDM4E 3804/4885ATM 3015/4885L3MBTL1 297/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 KDM4E 3804/4885ATM 3015/4885L3MBTL1 297/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA KDM4E 2784/4885ATM 3303/4885L3MBTL1 251/4885
US-20150270494-A1 Terminally Activated Delayed Fluorescence Material, A Method Of Synthesizing The Same and An OLED Device Using The Same OCIAD1, OCIAD2, OGFOD1 KDM4E 3472/4885ATM 3440/4885L3MBTL1 1887/4885
US-20150141642-A1 LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, RPLP0 KDM4E 3305/4885ATM 1950/4885L3MBTL1 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.