Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349632 | 0.81 | PGR (0.47) | PGRARKDM4EALDH1A1GAA | |
| SCHEMBL24584642 | 0.79 | ALDH1A1 (0.60) | PGRMAOAKDM4EALDH1A1GAA | |
| SCHEMBL12801020 | 0.74 | DYRK1A (0.46) | KDM4EALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL3419967 | 0.70 | MAOA (0.56) | PGRARMAOAKDM4EALDH1A1 | |
| SCHEMBL91929 | 0.70 | MAOA (0.56) | PGRARMAOAKDM4EALDH1A1 | |
| SCHEMBL25092558 | 0.70 | PGR (0.42) | PGRARKDM4EALDH1A1GAA | |
| Nitrogen SCHEMBL28849677 | 0.69 | CA1 (0.69) | KDM4ENPC1RAB9ATP53MAPK1 | |
| SCHEMBL197522 | 0.68 | CA1 (0.79) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL9151672 | 0.68 | CA1 (0.79) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL6733562 | 0.68 | CA1 (0.79) | KDM4EALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |