SCHEMBL16716059

SCHEMBL16716059

Cc1cnc(-c2ccccc2C)cc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 12/20 0.51
CYP2C19 P33261 9/20 0.51
CYP2D6 P10635 7/20 0.51
CYP3A4 P08684 7/20 0.51
CLK4 Q9HAZ1 6/20 0.51
ALDH1A1 P00352 4/20 0.51
HSD17B10 Q99714 2/20 0.51
ALOX15 P16050 1/20 0.51
IDO1 P14902 1/20 0.48
METAP2 P50579 1/20 0.48
MAPK1 P28482 3/20 0.47
TSHR P16473 2/20 0.47
TP53 P04637 1/20 0.44
HIF1A Q16665 1/20 0.44
MAPT P10636 3/20 0.43
HPGD P15428 3/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2187672 0.86 CYP1A2 (0.50) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL13843770 0.82 IDO1 (0.44) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL25543839 0.82 CYP1A2 (0.47) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL3424160 0.82 IDO1 (0.55) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL23879670 0.81 CYP1A2 (0.46) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL16716060 0.81 LDHA (0.50) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL807820 0.80 NPC1 (0.62) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL24851613 0.80 CYP1A2 (0.45) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL23879672 0.80 NOS3 (0.49) CYP1A2CYP2C19CYP2D6CYP3A4CLK4
SCHEMBL19373713 0.80 CYP1A2 (0.45) CYP1A2CYP2C19CYP2D6CYP3A4CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-11839141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-11 US disclosed
WO-2020036375-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-02-20 WO disclosed
WO-2019215426-A1 PROCESS FOR FORMING A CARBON-CARBON BOND THE UNIVERSITY OF MANCHESTER (GB) 2019-11-14 WO disclosed
WO-2019215427-A1 PROCESS FOR FORMING A CARBON-CARBON BOND THE UNIVERSITY OF MANCHESTER (GB) 2019-11-14 WO disclosed
EP-3000816-B1 A FIRST DEVICE COMPRISING IRIDIUM COMPLEXES WITH AZA-BENZO FUSED LIGANDS UNIVERSAL DISPLAY CORP (US) 2017-12-20 EP disclosed
EP-3220441-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-09-20 EP disclosed
EP-3205658-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-08-16 EP disclosed
EP-2874192-B1 Organic eletroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-05-10 EP disclosed
US-20150137096-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
EP-2874192-A2 Organic eletroluminescent materials and devices Universal Display Corporation (US) 2015-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR CYP1A2 3956/4885CYP2C19 4120/4885CYP2D6 3017/4885
US-20230337522-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LBR CYP1A2 3900/4885CYP2C19 4127/4885CYP2D6 3549/4885
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 CYP1A2 1308/4885CYP2C19 3138/4885CYP2D6 2945/4885
US-11839141-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 CYP1A2 471/4885CYP2C19 1273/4885CYP2D6 821/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP CYP1A2 1152/4885CYP2C19 1396/4885CYP2D6 1656/4885
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG CYP1A2 678/4885CYP2C19 1322/4885CYP2D6 1819/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR CYP1A2 1810/4885CYP2C19 2385/4885CYP2D6 2294/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 CYP1A2 2458/4885CYP2C19 2723/4885CYP2D6 3917/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 CYP1A2 1009/4885CYP2C19 2856/4885CYP2D6 2244/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR CYP1A2 1468/4885CYP2C19 2370/4885CYP2D6 965/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 CYP1A2 2224/4885CYP2C19 3389/4885CYP2D6 2100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.